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NCT04896242
Multimodal Assesment of Acute Cardiac Toxicity Induced by Thoracic Radiotherapy in Cancer Patients
trial in Radiotherapy; Complications in 47 participants. Completed in 1 April 2024.
31 October 2022
Quick facts
| Lead sponsor | Pontificia Universidad Catolica de Chile |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 47 |
| Start date | 9 January 2020 |
| Primary completion | 31 October 2022 |
| Estimated completion | 1 April 2024 |
| Sites | 1 location across Chile |
Conditions studied
- Radiotherapy; Complications — all drugs for Radiotherapy; Complications →
- Cardiotoxicity — all drugs for Cardiotoxicity →
- Cancer — all drugs for Cancer →
- Lung Cancer — all drugs for Lung Cancer →
Sponsor
Pontificia Universidad Catolica de Chile — full company profile →
Who can join
18 and older, any sex, with Radiotherapy; Complications or Cardiotoxicity. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to evaluate and compare the changes by two modalities: Imaging by Strain by Speckle Tracking and Magnetic Resonance versus soluble markers of cardiac dysfunction as early predictors of cardio-toxicity in cancer patients receiving low or high doses of radiotherapy.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Association of Sinoatrial Node Radiation Dose With Atrial Fibrillation and Mortality in Patients With Lung Cancer.
Kim KH, Oh J, Yang G, Lee J, et al · · 2022 · cited 59× · PMID 36136325 · DOI 10.1001/jamaoncol.2022.4202 -
Cardiovascular Magnetic Resonance Imaging in the Early Detection of Cardiotoxicity Induced by Cancer Therapies.
Wei X, Lin L, Zhang G, Zhou X. · · 2022 · cited 4× · PMID 36010197 · DOI 10.3390/diagnostics12081846 -
Multimodal assessment of acute cardiac toxicity induced by thoracic radiotherapy in cancer patients. Study protocol.
Merino T, Pinto MP, Orellana MP, Martinez G, et al · · 2021 · cited 4× · PMID 34663256 · DOI 10.1186/s12885-021-08823-3
Verify or expand the search:
- PubMed search for NCT04896242
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04896242 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Pontificia Universidad Catolica de Chile
- Last refreshed: 4 April 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04896242.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing