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NCT04892134

Evaluation of Clinical, Morphologic and Biochemical Markers in Multiple Sclerosis

Status unknown Last updated 19 October 2023
What this trial tests

trial testing blood sample in Multiple Sclerosis in 500 participants. Status unknown.

Timeline
3 October 2019
Primary endpoint
31 October 2024
31 October 2025

Quick facts

Lead sponsorMedical University of Graz
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment500
Start date3 October 2019
Primary completion31 October 2024
Estimated completion31 October 2025
Sites1 location across Austria

Drugs / interventions tested

Conditions studied

Sponsor

Medical University of Graz

Who can join

Adults 18 to 85, any sex, with Multiple Sclerosis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

By combining clinical, morphological and biochemical markers a better understanding of the formation and progression of multiple sclerosis (MS) should be obtained

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Coenzyme A fueling with pantethine limits autoreactive T cell pathogenicity in experimental neuroinflammation.
    Angiari S, Carlucci T, Budui SL, Bach SD, et al · · 2024 · cited 2× · PMID 39501296 · DOI 10.1186/s12974-024-03270-w
  2. Targeting pyruvate kinase M2 (PKM2) reduces T cell pathogenicity in multiple sclerosis.
    Ellmeier E, Schnabl A, Meissel J, Stracke A, et al · · 2026 · PMID 42208151 · DOI 10.1016/j.ebiom.2026.106314
  3. Time-Varying Brain Functional Reconfiguration Patterns Associated With Fatigue in Multiple Sclerosis.
    Hechenberger S, Broeders TAA, Bet MDA, Helmlinger B, et al · · 2026 · PMID 41797387 · DOI 10.1002/hbm.70480
  4. Association of CSF Kappa-Free Light Chains With Cortical and Periventricular Brain Damage in Multiple Sclerosis.
    Damulina A, Opriessnig P, Pirpamer L, Demjaha R, et al · · 2025 · PMID 41289552 · DOI 10.1212/wnl.0000000000214433

Verify or expand the search:

Other trials of blood sample

Trials testing the same drug.

Other recruiting trials for Multiple Sclerosis

Currently open trials in the same condition.

Other Medical University of Graz trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04892134.

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