NCT04886414

Home-based Care and Hand Hygiene Interventions in Honduras

Completed NA Last updated 14 May 2025

What this trial tests

NA trial testing Phone-based monitoring in Covid19 in 1,821 participants. Completed in 28 February 2023.

Timeline

31 March 2022

Primary endpoint
15 January 2023

28 February 2023

Quick facts

Lead sponsor	Brigham and Women's Hospital
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	factorial
Masking	none
Primary purpose	health services research
Enrollment	1,821
Start date	31 March 2022
Primary completion	15 January 2023
Estimated completion	28 February 2023
Sites	1 location across Honduras

Drugs / interventions tested

• Phone-based monitoring
• Oxygen saturation monitoring
• Alcohol-based hand sanitizer

Conditions studied

• Covid19 — all drugs for Covid19 →

Sponsor

Brigham and Women's Hospital

Who can join

45 and older, any sex, with Covid19. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study aims to enroll patients with acute infection with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) who do not meet criteria for hospital admission according to protocols developed by the Honduras Ministry of Health (MOH). Patients who are triaged to home must also be over the age of 60 years or have one high risk comorbidity and be over 45 years in order to meet inclusion criteria. These patients will be randomly assigned to one of four home-based care strategies, which may or may not include regular blood oxygenation monitoring and provision of alcohol-based hand-rub. Patients will be followed until resolution of their acute illness, and data will be collected on feasibility, impact and acceptance of the intervention. Some patients will be followed for up to one year to monitor for post-Coronavirus Disease 2019 (COVID-19) symptoms.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

1. Impact of self-administered pulse oximetry among non-hospitalized patients at risk of severe COVID-19 in Honduras: A pragmatic, cluster-randomized trial with temporal clustering.
   Roberts KW, Alvarez B, de St Aubin M, Diaz O, et al · · 2025 · PMID 41202024 · DOI 10.1371/journal.pgph.0004618
2. Impact of self-administered pulse oximetry among non-hospitalized patients at risk of severe COVID-19 in Honduras: A pragmatic, block-randomized trial
   Roberts KW, Alvarez B, de St. Aubin M, Diaz O, et al · · 2025 · DOI 10.1101/2025.04.23.25326278