NCT04885881 is a NA clinical trial of Ozone therapy in Myofascial Pain Syndrome, sponsored by Gaziler Physical Medicine and Rehabilitation Education and Research Hospital.

What drugs are being tested in NCT04885881?

Interventions in NCT04885881: Ozone therapy, Lidocaine injection group.

What condition does NCT04885881 study?

NCT04885881 studies Myofascial Pain Syndrome, Myofascial Trigger Point Pain.

Is NCT04885881 still recruiting?

NCT04885881 is currently completed. Last updated 18 January 2022.

Last reviewed 2022-01-18 · How we verify

NCT04885881

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Effectiveness of Ozone (O2-O3) Injections in the Treatment of Myofascial Pain Syndrome

Completed NA Last updated 18 January 2022

What this trial tests

NA trial testing Ozone therapy in Myofascial Pain Syndrome in 46 participants. Completed in 1 December 2021.

Timeline

15 April 2021

Primary endpoint
1 December 2021

1 December 2021

Quick facts

Lead sponsor	Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	46
Start date	15 April 2021
Primary completion	1 December 2021
Estimated completion	1 December 2021
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

Ozone therapy — full drug profile →
Lidocaine injection group

Conditions studied

Myofascial Pain Syndrome — all drugs for Myofascial Pain Syndrome →
Myofascial Trigger Point Pain — all drugs for Myofascial Trigger Point Pain →

Sponsor

Gaziler Physical Medicine and Rehabilitation Education and Research Hospital

Who can join

Adults 18 to 65, any sex, with Myofascial Pain Syndrome or Myofascial Trigger Point Pain. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Ozone (O2-O3) has been used as a supportive therapy in various musculoskeletal diseases such as lumbosacral disc herniation, knee osteoarthritis, meniscus injury, shoulder pathologies.The aim of this study is to investigate the effectiveness of ozone (O2-O3) injection applied to the trigger point in the treatment of myofascial pain syndrome.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Comparison of the efficacy of oxygen-ozone and lidocaine injections in the treatment of myofascial pain syndrome: A randomized clinical trial.
Korkmaz N, Örücü Atar M, Uyar Köylü S, Aslan SG, et al · · 2023 · cited 5× · PMID 37674800 · DOI 10.5606/tftrd.2023.11516

Verify or expand the search:

Other trials of Ozone therapy

Trials testing the same drug.

NCT07069153 — Laser vs Ozone Therapy for Oral Mucositis in Cancer Patients · NA · completed
NCT07035522 — Ozone Therapy for Women With Endometriosis · NA · not yet recruiting
NCT06954870 — Effect of Systemic and Local Ozone Therapy in Lipedema · NA · completed
NCT06706544 — Ozone Treatment in Paresthesia (Numbness, Tingling) Secondary to Chemotherapy-induced Peripheral Neuropathy · Phase 2, PHASE3 · recruiting
NCT06799351 — Gut Microbiome Profiles in Patients with Chemotherapy-induced Neuropathy in the RCT OzoParQT (NCT06706544). · Phase 2, PHASE3 · recruiting

Other recruiting trials for Myofascial Pain Syndrome

Currently open trials in the same condition.

NCT07511751 — COMPARISON OF THREE TREATMENT MODALITIES İN MYOFASCIAL PAIN SYNDROME · NA · recruiting
NCT07045324 — Effect of Vagus Nerve Stimulation on Trapezius Trigger Point · NA · active not recruiting

Other Gaziler Physical Medicine and Rehabilitation Education and Research Hospital trials

Trials by the same sponsor.

NCT07207694 — WhatsApp-Based Education Program for Stroke Patients · NA · not yet recruiting
NCT07472543 — Impact of Virtual Reality (VR) Based Exercises on Lower Limb Lymphedema Outcomes (LELO) · NA · recruiting
NCT07507357 — Tidal Model Nursing for TBI Caregivers · NA · completed
NCT07059468 — Osteoporosis After Stroke · completed
NCT06917027 — Comparison of Mobile Education and Face-to-Face Intermittent Catheterization Education · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04885881 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Last refreshed: 18 January 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04885881.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing