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NCT04884607
Autonomic Nerve Stimulation Using External Auditory Canal Electrodes
NA trial testing subthreshold low-level autonomic nerve stimulation using external auditory canal electrodes in Cardiac Arrhythmia in 12 participants. Completed in 28 February 2022.
31 December 2021
Quick facts
| Lead sponsor | Seoul National University Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 12 |
| Start date | 1 August 2021 |
| Primary completion | 31 December 2021 |
| Estimated completion | 28 February 2022 |
| Sites | 1 location across South Korea |
Drugs / interventions tested
- subthreshold low-level autonomic nerve stimulation using external auditory canal electrodes
Conditions studied
- Cardiac Arrhythmia — all drugs for Cardiac Arrhythmia →
- Cardiovascular Diseases — all drugs for Cardiovascular Diseases →
Sponsor
Seoul National University Hospital
Who can join
20 and older, any sex, with Cardiac Arrhythmia or Cardiovascular Diseases. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
* Purpose of the study This study aimed to investigate electrocardiogram measurement and subthreshold low-level autonomic nerve stimulation using external auditory canal electrodes among healthy adult participants * Study design Prospective, single-center, interventional, single-arm design * Study participants A total of 12 healthy adult participants without cardiovascular diseases will be recruited. * Study methods 1. Participant enrollment Study participants will be recruited by advertisement posters announced at the lobby of the hospital 2. Evaluation of electrocardiogram measurement from external auditory canal electrodes Participants are required to attach specially designed external auditory canal electrodes to their both ears to record electrocardiogram. Both electrocardiogram from the precordium and the ear would be simultaneously recorded and compared. 3. Evaluation of low-level autonomic nerve stimulation using external auditory canal Using the electrodes described above, Arnold's nerve will be stimulated with low-level electric impulses using TENS device. During and after the stimulation, heart rate variability will be measured to investigate the impact of nerve stimulation on autonomic function modulation on the heart.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04884607
- Europe PMC full search
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04884607 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Seoul National University Hospital
- Last refreshed: 18 April 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04884607.
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