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NCT04878991
Overture Metabolomics Non-Selection Study
trial testing Overture Metabolomics Embryo Selection in Infertility in 410 participants. Status unknown.
30 January 2024
Quick facts
| Lead sponsor | Overture Life |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 410 |
| Start date | 5 May 2021 |
| Primary completion | 30 January 2024 |
| Estimated completion | 30 January 2024 |
| Sites | 2 locations across United States, Spain |
Drugs / interventions tested
- Overture Metabolomics Embryo Selection
Conditions studied
- Infertility — all drugs for Infertility →
Sponsor
Overture Life
Who can join
Adults 18 to 50, female only, with Infertility. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
In this study, study investigators will collect embryo culture media on day 5 of vitro fertilization (IVF) culture, prior to vitrification and embryo transfer for testing via Metabolomic screening. Metabolomics is a new, non-invasive method of embryo selection which involves testing discarded embryo culture media for analytes secreted by the developing embryo. These analytes can be used to determine the implantation potential, and ploidy, of the embryo. This study will take place at multiple locations in the United States and Spain.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
A Mini-Review Regarding the Clinical Outcomes of In Vitro Fertilization (IVF) Following Pre-Implantation Genetic Testing (PGT)-Next Generation Sequencing (NGS) Approach.
Doroftei B, Ilie OD, Anton N, Armeanu T, et al · · 2022 · cited 10× · PMID 36010262 · DOI 10.3390/diagnostics12081911
Verify or expand the search:
- PubMed search for NCT04878991
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Overture Metabolomics Embryo Selection
Trials testing the same drug.
- NCT04976920 — Metabolomics Non Selection Study - Vitrolife Media · unknown
Other recruiting trials for Infertility
Currently open trials in the same condition.
- NCT07074015 — IntelliWell: An AI-Assisted Imaging Platform for Detection and Location of Ultra-Rare Testicular Sperm in Surgical Speci · NA · recruiting
- NCT07358468 — Impact Of FET Preparation Protocol On Endometrial Peristalsis: A Prospective Cohort Study · recruiting
- NCT07340827 — A Study to Compare the Efficacy and Safety of Follitropin Alfa/Lutropin Alfa Versus hMG in Japanese Participants With LH · Phase 3 · recruiting
- NCT07369362 — To Investigate if the Harvester® Improves Sperm Motility and Blastocyst Utilization (the Percent of Fertilized Eggs That · NA · active not recruiting
- NCT07153367 — Using a Fixed Dosage of Follitropin Delta for Ovarian Stimulation for Intrauterine Insemination: Rekovelle for Intrauter · Phase 2 · recruiting
Other Overture Life trials
Trials by the same sponsor.
- NCT06853418 — Paired Non-inferiority Study Comparing Overture Semi-automated Vitrification System ("DaVitri") to Standard Manual Proce · NA · recruiting
- NCT05607771 — DaVitri: Semi-Automated Vitrificacion Clinical Study · NA · unknown
- NCT05633316 — Automated Intracytoplasmic Sperm Injection (ICSIA) · NA · unknown
- NCT04976920 — Metabolomics Non Selection Study - Vitrolife Media · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04878991 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Overture Life
- Last refreshed: 14 November 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04878991.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing