Last reviewed · How we verify
NCT04874532
A Study to Improve Diabetes Management Among Adults Experiencing Severe Hypoglycemia
NA trial testing Community Paramedic Program in Diabetes in 150 participants. Suspended.
31 December 2026
Quick facts
| Lead sponsor | Mayo Clinic |
|---|---|
| Phase | NA |
| Status | Suspended |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | health services research |
| Enrollment | 150 |
| Start date | 4 June 2021 |
| Primary completion | 31 December 2026 |
| Estimated completion | 31 December 2026 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Community Paramedic Program
- Education Material
Conditions studied
- Diabetes — all drugs for Diabetes →
- Hypoglycemia — all drugs for Hypoglycemia →
- Diabetes Type 1 — all drugs for Diabetes Type 1 →
- Diabetes Type 2 — all drugs for Diabetes Type 2 →
Sponsor
Mayo Clinic
Who can join
18 and older, any sex, with Diabetes or Hypoglycemia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This pilot study will assess the feasibility, preliminary efficacy, and acceptability of the Diabetes-REM (Rescue, Engagement, and Management), a comprehensive patient-centered intervention delivered by community paramedics in the community setting to improve diabetes self-management, prevent recurrent hypoglycemia, reduce diabetes distress, and improve quality of life among adults in southeast Minnesota who have experienced severe hypoglycemia.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Diabetes rescue, engagement, and management (D-REM) for hypoglycemia: Clinical trial protocol of a community paramedic program to improve diabetes management among adults with severe hypoglycemia.
Bhagra S, Ducharme-Smith AL, Juntunen MB, Liedl CP, et al · · 2025 · cited 2× · PMID 40489473 · DOI 10.1371/journal.pone.0322177
Verify or expand the search:
- PubMed search for NCT04874532
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04874532 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Mayo Clinic
- Last refreshed: 9 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04874532.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing