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NCT04874285
Use of Dietary Supplements in Patients at Risk of Abortion Treated With Progesterone.
NA trial testing HA in Pregnancy, High Risk in 63 participants. Completed in 11 May 2023.
30 May 2022
Quick facts
| Lead sponsor | Lo.Li.Pharma s.r.l |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 63 |
| Start date | 3 May 2021 |
| Primary completion | 30 May 2022 |
| Estimated completion | 11 May 2023 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- HA — full drug profile →
Conditions studied
- Pregnancy, High Risk — all drugs for Pregnancy, High Risk →
Sponsor
Lo.Li.Pharma s.r.l
Who can join
Adults 18 to 50, female only, with Pregnancy, High Risk. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The trial aims to investigate the effect of supplementation with hyaluronic acid, alpha-lipoic acid, magnesium, vitamin D and vitamin B6 in progesterone-treated pregnant women with risk factors for abortion.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The Association of High-Molecular-Weight Hyaluronic Acid (HMWHA), Alpha Lipoic Acid (ALA), Magnesium, Vitamin B6, and Vitamin D Improves Subchorionic Hematoma Resorption in Women with Threatened Miscarriage: A Pilot Clinical Study.
Porcaro G, Laganà AS, Neri I, Aragona C. · · 2024 · cited 3× · PMID 38337402 · DOI 10.3390/jcm13030706
Verify or expand the search:
- PubMed search for NCT04874285
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Pregnancy, High Risk
Currently open trials in the same condition.
- NCT05388643 — Early Detection of Gestational Diabetes Mellitus in Pregnancy · NA · recruiting
- NCT06654713 — Commercial or Open Source Closed Loop Impact on Pregnancy Study · recruiting
- NCT05317585 — Continuous Glucose Monitor Use in Pregnancy · NA · recruiting
- NCT05790252 — Transdermal Patch for BupRenorphine Induction DurinG PrEgnancy (Patch BRIDGE) · Phase 3 · recruiting
- NCT05909046 — A Randomized Controlled Trial of Diabetes Screening Immediately Postpartum (DIP) and Follow Up PP CARE · NA · recruiting
Other Lo.Li.Pharma s.r.l trials
Trials by the same sponsor.
- NCT07257770 — Local Treatment of Breast Pain Based on the Daily Use of a Topical Gel · NA · recruiting
- NCT06715527 — Treatment of Women With Hyperandrogenic PCOS With Two Different Ratios of Myo-inositol:D-chiro-inositol: A Comparison · NA · completed
- NCT06639698 — Treatment of Women With PCOS of Phenotype D · NA · completed
- NCT05674318 — The Effect of Alpha-lactalbumin on Microbiota Composition · NA · completed
- NCT05678114 — Inositol Treatment in Different Type of PCOS Phenotype · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04874285 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Lo.Li.Pharma s.r.l
- Last refreshed: 3 November 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04874285.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing