Who is sponsoring NCT04871763?

NCT04871763 is sponsored by University of Pavia.

What drugs are being tested in NCT04871763?

Interventions in NCT04871763: Retainers' Cleansing with Geldis®, Retainers' Cleansing with tablets, Retainers' cleansing with water.

What condition does NCT04871763 study?

NCT04871763 studies Orthodontic Appliance Complication.

Is NCT04871763 still recruiting?

NCT04871763 is currently completed. Last updated 21 December 2021.

Last reviewed 2021-12-21 · How we verify

NCT04871763

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Assessment of Bacterial Loads of Essix Retainers in Patients Under Retention Therapy

Completed NA Last updated 21 December 2021

What this trial tests

NA trial testing Retainers' Cleansing with Geldis® in Orthodontic Appliance Complication in 15 participants. Completed in 18 December 2021.

Timeline

12 May 2021

Primary endpoint
15 December 2021

18 December 2021

Quick facts

Lead sponsor	University of Pavia
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	15
Start date	12 May 2021
Primary completion	15 December 2021
Estimated completion	18 December 2021
Sites	1 location across Italy

Drugs / interventions tested

Retainers' Cleansing with Geldis®
Retainers' Cleansing with tablets
Retainers' cleansing with water

Conditions studied

Orthodontic Appliance Complication — all drugs for Orthodontic Appliance Complication →

Sponsor

University of Pavia

Who can join

Adults 18 to 50, any sex, with Orthodontic Appliance Complication. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of this study is to investigate the bacterial loads present on essix retainers in patients' contention therapy. Patients are randomly divided into three groups, depending on the product used for the cleansing of the retainers: Geldis, Polident tablets and water. Microbiological samples were taken from the retainers at the baseline, after 1 and after 2 months, together with Bleeding Index, Plaque Index, BEWE Index and Schiff Air Sensitivity test.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Assessment of the Bacterial Loads of Vacuum-Thermoformed Removable Retainers (VTRR) in Patients under Retention Therapy: A Randomized Clinical Trial.
Butera A, Gallo S, Pascadopoli M, Sfondrini B, et al · · 2022 · cited 1× · PMID 35885766 · DOI 10.3390/healthcare10071239

Verify or expand the search:

Other recruiting trials for Orthodontic Appliance Complication

Currently open trials in the same condition.

NCT06944860 — Microbial Adherence, Surface Roughness, Effectiveness and Impact on Patients Between Conventional and 3D Printed Twin Bl · NA · recruiting
NCT06573996 — The Effect of Intraoral Transcutaneous Electrical Nerve Stimulation in Orthodontics Pain · NA · recruiting
NCT06502886 — Evaluation of The Stability of Orthodontic Treatment After First Premolar Extraction Using Combined Retention Protocol · NA · recruiting
NCT05733676 — Comparison of MI Paste Plus and Resin Infiltration in White Spot Lesions Following Orthodontic Treatment · NA · recruiting

Other University of Pavia trials

Trials by the same sponsor.

NCT07491536 — Ozone Therapy With Biomimetic Oral Care for Cancer-Related Oral Mucositis · NA · recruiting
NCT07421128 — The Pause, Learn, and Activate Yourself (PLAY) · NA · not yet recruiting
NCT07199712 — Ozone Therapy for Oral Mucositis in Patients Receiving Head and Neck Cancer Radio- and Chemotherapy · NA · completed
NCT07088653 — Comparison of 0.12% Chlorhexidine and MicroRepair ABX Mouthwash in Gingivitis Management · NA · completed
NCT07140146 — Trehalose vs Glycine Air-Polishing in Peri-Implant Mucositis Treatment · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04871763 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Pavia
Last refreshed: 21 December 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04871763.

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