NCT04863482 (SCOTCH) is a NA clinical trial of IOC in Cholecystitis; Gallstone, sponsored by Università Politecnica delle Marche.

Who is sponsoring NCT04863482?

NCT04863482 is sponsored by Università Politecnica delle Marche.

What drugs are being tested in NCT04863482?

Interventions in NCT04863482: IOC.

What condition does NCT04863482 study?

NCT04863482 studies Cholecystitis; Gallstone.

Is NCT04863482 still recruiting?

NCT04863482 is currently status unknown. Last updated 8 October 2021.

Last reviewed 2021-10-08 · How we verify

NCT04863482: SCOTCH

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Safety of Laparoscopic ChOlecystectomy Performed by Trainee Surgeons With Different CHolangiographic Techniques

Status unknown NA Last updated 8 October 2021

What this trial tests

NA trial testing IOC in Cholecystitis; Gallstone in 1,500 participants. Status unknown.

Timeline

1 June 2021

Primary endpoint
31 December 2021

31 December 2021

Quick facts

Lead sponsor	Università Politecnica delle Marche
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	non randomized
Design	parallel
Masking	none
Primary purpose	prevention
Enrollment	1,500
Start date	1 June 2021
Primary completion	31 December 2021
Estimated completion	31 December 2021
Sites	1 location across Italy

Drugs / interventions tested

IOC — full drug profile →

Conditions studied

Cholecystitis; Gallstone — all drugs for Cholecystitis; Gallstone →

Sponsor

Università Politecnica delle Marche — full company profile →

Who can join

Adults 18 to 99, any sex, with Cholecystitis; Gallstone. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Laparoscopic cholecystectomy (LC) gained popularity among general surgeons in 1990s and rapidly become one of the most commonly performed procedures in digestive surgery, with more than one million cholecystectomies being performed in the United States per year. LC remains also one of the most commonly performed procedure by general surgeons during the training period. Even if previous report LC cases performed by surgical trainees (ST) are not associated with higher operative morbidity, the length of operative time is significantly increased when compared with that of LC cases performed by attending surgeons, due, most of all, to difficulties in identifying the anatomical structure, and this sometimes leads to an attending surgeon taking away the case from the trainee. Furthermore, despite the fact that LC has proven to be a safe procedure, the rate of common bile duct (BDI) injury still remains unacceptably high even in the hands of minimally invasive trained surgeons ranging from 0.2 to 1.5% in individual reports, much higher than initial reports, associated with significant morbidity and mortality, lower quality of life and increased costs, related to additional health care measures, loss of work days, and insurance claims. The aim of this study is to address which of the techniques now available could be addressed as the best option in a training setting to enhance the learning curve, to ideally build a safe cholecystectomy training program and virtually eliminate the risk of BDI due to anatomic misinterpretation during the training period.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Safety of laparoscopic cholecystectomy performed by trainee surgeons with different cholangiographic techniques (SCOTCH): a prospective non-randomized trial on the impact of fluorescent cholangiography during laparoscopic cholecystectomy performed by trainees.
Ortenzi M, Corallino D, Botteri E, Balla A, et al · · 2024 · cited 6× · PMID 38135732 · DOI 10.1007/s00464-023-10613-w

Verify or expand the search:

Other trials of IOC

Trials testing the same drug.

NCT03922724 — Allogeneic Hematopoietic Cell Transplantation for Peripheral T Cell Lymphoma · Phase 2 · recruiting

Other recruiting trials for Cholecystitis; Gallstone

Currently open trials in the same condition.

NCT06824506 — Ultrasound for Postop Lung Issues in Low-Flow Anesthesia · recruiting
NCT06656299 — EOIB for Laparoscopic Cholecystectomy · NA · recruiting
NCT06349863 — Dutch Cholecystitis Snapshot Study · recruiting
NCT06045546 — A (5-5-5-8) Technique for Laparoscopic Cholecystectomy · NA · active not recruiting

Other Università Politecnica delle Marche trials

Trials by the same sponsor.

NCT07189520 — 1. SAFE-AI ONCO-TRACK: Multimodal GenAI for Early Detection of Minimal Residual Disease and Recurrence in Gastrointestin · not yet recruiting
NCT07404475 — Microcirculation and Coagulopathy in Sepsis · completed
NCT06272448 — teleRehabilitation for pAtients With ParkInson's Disease at Any mOment · NA · completed
NCT05267834 — Adenocarcinoma of the Uterine Cervix and HPV · completed
NCT05110950 — Endobronchial Ultrasound Needle Aspiration With and Without Suction · NA · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04863482 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Università Politecnica delle Marche
Last refreshed: 8 October 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04863482.

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