Last reviewed · How we verify
NCT04861493
Cathelicidin LL-37 Levels in the GCF and the Saliva of Smokers and Non-smokers With Stage III,IV Periodontitis
trial in Smoking Reduction in 60 participants. Completed in 15 April 2021.
23 February 2021
Quick facts
| Lead sponsor | Cairo University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 60 |
| Start date | 23 February 2021 |
| Primary completion | 23 February 2021 |
| Estimated completion | 15 April 2021 |
| Sites | 1 location across Egypt |
Conditions studied
- Smoking Reduction — all drugs for Smoking Reduction →
Sponsor
Cairo University
Who can join
Eligibility, any sex, with Smoking Reduction. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Periodontitis is considered an inflammatory disease that results in the disruption of oral hemeostasis and is associated with the presence of dental plaque influenced by genetic and environmental factors. It is well-establised that smokers have an increased severity of periodontal disease,a higher prevalance of tooth loss and total edentulism.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Cathelicidins: Opportunities and Challenges in Skin Therapeutics and Clinical Translation.
Dzurová L, Holásková E, Pospíšilová H, Schneider Rauber G, et al · · 2024 · cited 8× · PMID 39858288 · DOI 10.3390/antibiotics14010001
Verify or expand the search:
- PubMed search for NCT04861493
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Smoking Reduction
Currently open trials in the same condition.
- NCT07129590 — Trauma-Informed Care for Smoking Cessation for Pregnancy · NA · recruiting
- NCT06693700 — A Study Evaluating the Use of an Indoor Air Quality Monitor to Promote a Smoke-free Home · NA · recruiting
- NCT06675526 — Detour: a Smartphone Game to Help Youth Quit Smoking · NA · recruiting
- NCT06458205 — Impact of Multi-Component Interventions on High-Risk COPD Smokers · NA · active not recruiting
- NCT06311162 — Early Life Intervention in Pediatrics Supported by E-health - SMOKE · NA · recruiting
Other Cairo University trials
Trials by the same sponsor.
- NCT04155528 — Effect of Music Therapy on Postoperative Health Outcomes · NA · not yet recruiting
- NCT07363239 — CBCT-Based Safety Distance for Implant Placement Near the Inferior Alveolar Canal · not yet recruiting
- NCT07374575 — Egyptian Dental Professionals' Perspectives on the Oral Microbiome and Exosomes · not yet recruiting
- NCT07381153 — In-Vitro Cytotoxicity Assessment of INOX (Nanoksa G Plus) Polymer Discs · not yet recruiting
- NCT07375394 — 3D-Printed Extraoral Camera for Standardized Dental Photography · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04861493 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Cairo University
- Last refreshed: 27 April 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04861493.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing