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NCT04858360
Inhibition of Non-histaminergic Pruritus Applied Using 3 Different Pruritogens
NA trial testing Emla 1 hour in Itch in 22 participants. Completed in 1 October 2022.
1 August 2022
Quick facts
| Lead sponsor | Aalborg University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 22 |
| Start date | 15 November 2021 |
| Primary completion | 1 August 2022 |
| Estimated completion | 1 October 2022 |
| Sites | 1 location across Denmark |
Drugs / interventions tested
- Emla 1 hour — full drug profile →
- EMLA 3 hours — full drug profile →
- Vehicle cream for 1 hour
- Vehicle cream for 3 hours
- Cowhage
Conditions studied
- Itch — all drugs for Itch →
Sponsor
Aalborg University
Who can join
Adults 18 to 60, any sex, with Itch. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
With this experiment, we want to use to investigate whether repeated application of EMLA cream as a tool to modulate non-histaminergic itching, which is produced using small needles from the plant mucuna pruriens (it is known that antihistamine does not attenuate this form of itch) and we want to compare the effect of short (1 hour) and prolonged (3 hours) application of EMLA. The sub-project takes place in 3 sessions over a period of 3 consecutive days (24 hours apart). All sessions will be identical.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04858360
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
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Related trials
Other recruiting trials for Itch
Currently open trials in the same condition.
- NCT07122973 — Topographical Distribution of Itch and Pain Receptors · NA · recruiting
- NCT06997926 — Identification of the Mechanism of Non-histaminergic Itch Inducing Epigenetic Changes · NA · active not recruiting
- NCT06503510 — Role of Interleukin-13 Pathways on Pain and Itch Sensitivity · NA · recruiting
- NCT06503523 — The Effects of Performing a Motor Imagery Task on Cortical Excitability During Acute Experimental Muscle Pain and Acute · NA · recruiting
Other Aalborg University trials
Trials by the same sponsor.
- NCT07580989 — Network Effects of Left M1 rTMS: A TMS-EEG Study · NA · recruiting
- NCT07395882 — A New Model to Induce Itch and Inflammation · NA · not yet recruiting
- NCT07395869 — Off-set Analgesia Induced by Cold Temperature · NA · not yet recruiting
- NCT07266103 — Mechanistic Study of Personalized rTMS in Chronic Pain · NA · not yet recruiting
- NCT07373392 — Effects of LP-LDL® on Lipid Metabolism, Glycemic Control, Inflammatory Markers, and Cognitive Function in Individuals Wi · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04858360 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Aalborg University
- Last refreshed: 18 January 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04858360.
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