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NCT04858243
Engaging Men Through HIV Self-Testing With Differentiated Care to Improve ART Initiation and Viral Suppression Among Men in Malawi
NA trial testing Home-Based ART in Hiv in 930 participants. Status unknown.
31 March 2025
Quick facts
| Lead sponsor | University of California, Los Angeles |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 930 |
| Start date | 2 August 2021 |
| Primary completion | 31 March 2025 |
| Estimated completion | 30 June 2025 |
| Sites | 1 location across Malawi |
Drugs / interventions tested
- Home-Based ART
- Facility-Based ART
Conditions studied
- Hiv — all drugs for Hiv →
Sponsor
University of California, Los Angeles
Who can join
15 and older, any sex, with Hiv. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Men in sub-Saharan Africa who test HIV-positive continue to have poor ART initiation and retention outcomes. The proposed project will test a home-based ART intervention for men who are living with HIV compared to facility-based ART. Findings will provide essential information on how to best reach men across the testing and treatment continuum, a critical step to curbing the HIV epidemic.
Publications & conference data
7 peer-reviewed publications reference this trial (live from Europe PMC):
-
Engaging men through HIV self-testing with differentiated care to improve ART initiation and viral suppression among men in Malawi (ENGAGE): A study protocol for a randomized control trial.
Choko AT, Coates TJ, Mphande M, Balakasi K, et al · · 2023 · cited 7× · PMID 36827327 · DOI 10.1371/journal.pone.0281472 -
Developing a male-specific counselling curriculum for HIV treatment in Malawi.
Mphande M, Robson I, Hubbard J, Lungu E, et al · · 2025 · cited 1× · PMID 40734975 · DOI 10.12688/gatesopenres.16357.1 -
Core components of male-specific person-centred HIV care: a qualitative analysis from client and healthcare worker perspectives in Malawi.
Hubbard J, Mphande M, Robson I, Balakasi K, et al · · 2024 · cited 1× · PMID 40018627 · DOI 10.1136/bmjph-2024-001100 -
Implementing a male-specific ART counselling curriculum: a quality assessment with healthcare workers in Malawi.
Robson I, Mphande M, Lee J, Hubbard JA, et al · · 2024 · cited 1× · PMID 39039724 · DOI 10.1002/jia2.26270 -
Implementation of male-specific motivational interviewing in Malawi: an assessment of intervention fidelity and barriers to scale-up.
Holland KN, Hubbard J, Mphande M, Robson I, et al · · 2026 · PMID 41916615 · DOI 10.1136/bmjgh-2024-018269 -
Implementation of Male-Specific Motivational Interviewing in Malawi: An Assessment of Intervention Fidelity and Barriers to Scale-Up
Holland KN, Hubbard J, Mphande M, Robson I, et al · · 2024 · DOI 10.1101/2024.09.24.24314326 -
Engaging Men Through HIV Self-Testing with Differentiated Care to Improve ART Initiation and Viral Suppression among Men in Malawi (ENGAGE): a study protocol for a randomized control trial
Choko AT, Coates TJ, Mphande M, Balakasi K, et al · · 2022 · DOI 10.1101/2022.12.22.22283837
Verify or expand the search:
- PubMed search for NCT04858243
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Home-Based ART
Trials testing the same drug.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04858243 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of California, Los Angeles
- Last refreshed: 15 May 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04858243.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing