NCT04857242 is a NA clinical trial of Apnea test, alveolar recruitment in Brain Death, sponsored by Kiskunhalas Semmelweis Hospital the Teaching Hospital of the University of Szeged.

What drugs are being tested in NCT04857242?

Interventions in NCT04857242: Apnea test, alveolar recruitment.

What condition does NCT04857242 study?

NCT04857242 studies Brain Death.

Is NCT04857242 still recruiting?

NCT04857242 is currently completed. Last updated 20 February 2024.

Last reviewed 2024-02-20 · How we verify

NCT04857242

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Electrical Impedance Tomography Measurements During Apnea Test in Patients With Suspected Brain Death

Completed NA Last updated 20 February 2024

What this trial tests

NA trial testing Apnea test, alveolar recruitment in Brain Death in 10 participants. Completed in 13 April 2023.

Timeline

1 April 2021

Primary endpoint
13 April 2023

13 April 2023

Quick facts

Lead sponsor	Kiskunhalas Semmelweis Hospital the Teaching Hospital of the University of Szeged
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	diagnostic
Enrollment	10
Start date	1 April 2021
Primary completion	13 April 2023
Estimated completion	13 April 2023
Sites	1 location across Hungary

Drugs / interventions tested

Apnea test, alveolar recruitment

Conditions studied

Brain Death — all drugs for Brain Death →

Sponsor

Kiskunhalas Semmelweis Hospital the Teaching Hospital of the University of Szeged

Who can join

Adults 18 to 99, any sex, with Brain Death. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Apnea testing is the final decisive examination in the strictly regulated process of brain death assessment. There is no standardized method found in the literature for apnea testing except for the inspection of possible spontaneous chest movements. In addition, the test itself lasts for several minutes leading to the collapse of the lungs. Electrical impedance tomography (EIT) is a non-invasive, real-time monitoring technique, which is suitable for detecting changes in lung volumes during ventilation. With its help, one can examine the spontaneous initiation of inspiration, the development of atelectasis and the reopening of collapsed regions by mechanical ventilation. Furthermore, the apnea test provides for analysing the effect of changes in pulmonary perfusion on impedance in the absence of noise generated by ventilation.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Detection of spontaneous breathing during an apnea test in a patient with suspected brain death using electrical impedance tomography: a case report.
Chen R, Lovas A, Bakos P, Molnár T, et al · · 2024 · PMID 39285376 · DOI 10.1186/s12890-024-03283-4

Verify or expand the search:

Other recruiting trials for Brain Death

Currently open trials in the same condition.

NCT06640088 — Determining ICU Staffs Conceptions, Opinions, Views, Experiences and Reflection of Brain Death and Organ Donation · recruiting

Other Kiskunhalas Semmelweis Hospital the Teaching Hospital of the University of Szeged trials

Trials by the same sponsor.

NCT06359119 — Implementation of Apnoea Test for Patients With Suspected Brain Death · not yet recruiting
NCT06290310 — Assessment of Patient-ventilator Asynchrony by Electric Impedance Tomography · unknown
NCT04174014 — Optimal PEEP Titration Combining Transpulmonary Pressure Measurement and Electric Impedance Tomography · NA · unknown
NCT04141293 — Hemodynamic Effects of Changes in Transpulmonary Pressure During Recruitment Maneuver in Patients Under Pressure Support · NA · withdrawn

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04857242 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Kiskunhalas Semmelweis Hospital the Teaching Hospital of the University of Szeged
Last refreshed: 20 February 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04857242.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing