NCT04854018 is a Phase 4 clinical trial of Indocyanine green in Pediatric Renal Tumor, sponsored by Birmingham Women's and Children's NHS Foundation Trust.

Who is sponsoring NCT04854018?

NCT04854018 is sponsored by Birmingham Women's and Children's NHS Foundation Trust.

What drugs are being tested in NCT04854018?

Interventions in NCT04854018: Indocyanine green.

What condition does NCT04854018 study?

NCT04854018 studies Pediatric Renal Tumor, Metastatic Osteosarcoma, Metastatic Ewing Sarcoma, Pulmonary Metastasis, Rhabdomyosarcoma, Non-Rhabdo. Soft Tissue Sarcoma.

Is NCT04854018 still recruiting?

NCT04854018 is currently completed. Last updated 14 August 2023.

Last reviewed 2023-08-14 · How we verify

NCT04854018

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Indo-cyanine Green (ICG) in Paediatric Oncology MIS

Completed Phase 4 Last updated 14 August 2023

What this trial tests

Phase 4 trial testing Indocyanine green in Pediatric Renal Tumor in 20 participants. Completed in 30 September 2022.

Timeline

30 April 2021

Primary endpoint
30 September 2022

30 September 2022

Quick facts

Lead sponsor	Birmingham Women's and Children's NHS Foundation Trust
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	20
Start date	30 April 2021
Primary completion	30 September 2022
Estimated completion	30 September 2022
Sites	1 location across United Kingdom

Drugs / interventions tested

Indocyanine green (INDOCYANINE GREEN) — full drug profile →

Conditions studied

Pediatric Renal Tumor — all drugs for Pediatric Renal Tumor →
Metastatic Osteosarcoma — all drugs for Metastatic Osteosarcoma →
Metastatic Ewing Sarcoma — all drugs for Metastatic Ewing Sarcoma →
Pulmonary Metastasis — all drugs for Pulmonary Metastasis →

Sponsor

Birmingham Women's and Children's NHS Foundation Trust

Who can join

Adults 1 Day to 15, any sex, with Pediatric Renal Tumor or Metastatic Osteosarcoma. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Indo-cyanine green (ICG) is a dye that has been used for a variety of adult and paediatric uses since 1956. Over the past few years, near infrared (NIRF) technology has been developed which allow is use as a fluorescence agent during surgery. It has been used increasingly in the field of adult oncology surgery and has been shown to increase the efficacy of this surgery. The aim of this study is to evaluate the use of NIRF and ICG during specific minimally invasive surgery (MIS) procedures within paediatric oncology surgery. Their use will complement existing surgical techniques rather than replace them. Given the published advantages in adults this study aims to provide evidence of feasibility in the paediatric patients with cancer.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Indocyanine green

Trials testing the same drug.

NCT06164392 — Evaluation of Neuroma Perfusion with Indocyanine Green Fluorescence Angiography · Phase 4 · withdrawn
NCT06169735 — Does Fluorescence With or Without Indocyanine Green Improve Parathyroid Identification and Preservation · Phase 4 · recruiting
NCT06322862 — FLuorescence Guided Assessment of Mesenteric Ischemia in Emergency Surgery · NA · recruiting
NCT06227338 — ICG-fluorescence Imaging for Intraoperative Breast Cancer Margins Evaluation: a Dose-timing Study · NA · recruiting
NCT06939946 — Intraoperative Parathyroid Gland (PTG) Identification Using a Hand-Held Imager (HHI) · Phase 1 · terminated

Other Birmingham Women's and Children's NHS Foundation Trust trials

Trials by the same sponsor.

NCT05735977 — Nephrogreen. Appearances of Exvivo Renal Tumours Under Near-infrared · NA · completed
NCT05971563 — Amino Acid Kinetics of GMP-AA in Healthy Human Volunteers · NA · completed
NCT05702294 — Electronic Urinary Flowmeter to Improve Accuracy of Bladder Diaries . · NA · completed
NCT04906551 — Measuring Endometrial Blood Flow Using Laser Doppler: Acceptability & Reproducibility · unknown
NCT04751500 — The HYsteroscopic Miscarriage MaNagement Trial: A Pilot RCT Investigating a Novel Management Pathway for RPOC · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04854018 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Birmingham Women's and Children's NHS Foundation Trust
Last refreshed: 14 August 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04854018.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing