NCT04848181 is a EARLY_PHASE1 clinical trial of cyproterone acetate in Prostate Hyperplasia, sponsored by Benha University.

Who is sponsoring NCT04848181?

NCT04848181 is sponsored by Benha University.

What drugs are being tested in NCT04848181?

Interventions in NCT04848181: cyproterone acetate, finasteride, no treatment received.

What condition does NCT04848181 study?

NCT04848181 studies Prostate Hyperplasia.

Is NCT04848181 still recruiting?

NCT04848181 is currently completed. Last updated 21 July 2021.

Last reviewed 2021-07-21 · How we verify

NCT04848181

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Effect of Pre-operative Use of Finasteride Versus Cyproterone Acetate on Blood Loss With Transurethral Resection of Prostate

Completed EARLY_PHASE1 Last updated 21 July 2021

What this trial tests

EARLY_PHASE1 trial testing cyproterone acetate in Prostate Hyperplasia in 60 participants. Completed in 9 July 2020.

Timeline

1 July 2019

Primary endpoint
1 July 2020

9 July 2020

Quick facts

Lead sponsor	Benha University
Phase	EARLY_PHASE1
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	60
Start date	1 July 2019
Primary completion	1 July 2020
Estimated completion	9 July 2020
Sites	1 location across Egypt

Drugs / interventions tested

cyproterone acetate (CYPROTERONE ACETATE) — full drug profile →
finasteride (finasteride) — full drug profile →
no treatment received — full drug profile →

Conditions studied

Prostate Hyperplasia — all drugs for Prostate Hyperplasia →

Sponsor

Benha University

Who can join

Eligibility, male only, with Prostate Hyperplasia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Perioperative bleeding is the most common complication related to transurethral resection of prostate, the aim of the study is to compare the effect of pre-operative use of finasteride versus Cyproterone acetate on blood loss with mono polar TURP

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Regulation of HNRNP family by post-translational modifications in cancer.
Li B, Wen M, Gao F, Wang Y, et al · · 2024 · cited 13× · PMID 39366930 · DOI 10.1038/s41420-024-02198-7

Verify or expand the search:

Other trials of cyproterone acetate

Trials testing the same drug.

NCT00003653 — Hormone Therapy in Treating Patients With Rising PSA Levels Following Radiation Therapy for Prostate Cancer · Phase 3 · completed

Other recruiting trials for Prostate Hyperplasia

Currently open trials in the same condition.

NCT06865430 — Management of Dysuria and Irritative Symptoms After HoLEP: a Prospective Study Evaluating the Efficacy of Alpha-Blocker · NA · recruiting
NCT06834152 — Online Adaptive Stereotactic Body Radiotherapy for Localized Prostate Cancer (X-SMILE) · recruiting
NCT06224218 — Prostate Single Port & Laser Enucleation Comparison Trial · NA · recruiting
NCT05443451 — BETTY: BEnign Prostatic Hyperplasia Transperineal Targeted Microwave therapY · NA · recruiting
NCT06116851 — Prostate Metabolism, Cancer Risk and Gut Microbiota · recruiting

Other Benha University trials

Trials by the same sponsor.

NCT07526675 — Concomitant Trans-Perineal Prostate Biopsy and Ablation (Bioblation) for Prostate Cancer · NA · not yet recruiting
NCT07480031 — Determination of the Optimal Inspiratory Pressure to Decrease Incidence of Gastric Insufflation With Adequate Ventilatio · NA · not yet recruiting
NCT07465185 — Intrathecal Bupivacaine With or Without Dexmetomidine for Cesserian Delivery · Phase 2 · recruiting
NCT07467356 — Anterior Iliopsoas Space Block Versus PENG Block on Ease of Positioning for Spinal Anathesia in Patients Undergoing Hip · Phase 3 · recruiting
NCT07300787 — miRNA in Pediatric Gastritis · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04848181 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Benha University
Last refreshed: 21 July 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04848181.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing