Last reviewed · How we verify
NCT04844255: AcuteSS
Acute Salt Sensitivity of Blood Pressure
NA trial testing dietary salt in Blood Pressure in 132 participants. Completed in 28 February 2021.
28 February 2021
Quick facts
| Lead sponsor | Mulungushi University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 132 |
| Start date | 1 December 2020 |
| Primary completion | 28 February 2021 |
| Estimated completion | 28 February 2021 |
| Sites | 1 location across Zambia |
Drugs / interventions tested
- dietary salt
Conditions studied
- Blood Pressure — all drugs for Blood Pressure →
Sponsor
Mulungushi University
Who can join
18 and older, any sex, with Blood Pressure. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Dietary salt raises blood pressure in certain individuals immediately after ingestion (acute salt sensitivity; ASS) while not affecting others. It is hypothesized that ASS is a risk factor for hypertension. However, no thresholds or diagnostic guideline is available for ASS. This study is the first aim in the main study (HIPO CAP DITSH Study) aimed at determining the threshold or blood pressure cut-offs for ASS upon ingesting dietary salt.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Immediate pressor response to oral salt and its assessment in the clinic: a time series clinical trial.
Masenga SK, Pilic L, Hamooya BM, Nzala S, et al · · 2022 · cited 6× · PMID 36104796 · DOI 10.1186/s40885-022-00209-2 -
Erythrocyte glycocalyx sensitivity to sodium is associated with salt sensitivity of blood pressure in women but not men.
Masenga SK, Hamooya BM, Patel KP, Kirabo A. · · 2024 · cited 3× · PMID 38524849 · DOI 10.3389/fnut.2024.1334853
Verify or expand the search:
- PubMed search for NCT04844255
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Mulungushi University trials
Trials by the same sponsor.
- NCT04459741 — HIV, Immune Activation and Salt Sensitive Hypertension · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04844255 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Mulungushi University
- Last refreshed: 15 April 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04844255.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing