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NCT04841759

The Effects of a Multi-factorial Rehabilitation Program for Healthcare Workers Suffering From Post-COVID-19 Fatigue Syndrome

Completed NA Last updated 27 December 2021
What this trial tests

NA trial testing Exercise in COVID-19 in 46 participants. Completed in 22 December 2021.

Timeline
1 April 2021
Primary endpoint
3 December 2021
22 December 2021

Quick facts

Lead sponsorMedical University of Vienna
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationnon randomized
Designparallel
Maskingsingle
Primary purposesupportive care
Enrollment46
Start date1 April 2021
Primary completion3 December 2021
Estimated completion22 December 2021
Sites1 location across Austria

Drugs / interventions tested

Conditions studied

Sponsor

Medical University of Vienna

Who can join

Adults 18 to 65, any sex, with COVID-19. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The SARS-CoV2 pandemic has kept the world in suspense for over a year now. Almost 100 million people around the world have contracted COVID-19 to date and over 2 million people have died of COVID-19 by the end of January 2021. Despite the tragedy of these deaths, it must be pointed out at this point that the number of COVID-19 survivors is significantly larger. These COVID-19 survivors are now the focus of interest in rehabilitation measures, as it has been shown that survival of the disease does not go hand in hand with a complete cure. Thirty-five percent of all COVID-19 survivors and 87% of the COVID-19 survivors who were hospitalized in the course of their illness suffer from after-effects that are currently summarized as post-COVID fatigue syndrome also known as "Long-COVID". As health care workers are at higher risk of contracting SARS CoV2 and furthermore, considering their central role in the overcoming of this pandemic, a COVID-19 rehabilitation program for healthcare workers of the Medical University of Vienna, Austria as well as the General Hospital of Vienna, Austria - together the second-largest university-clinic in the world - was developed as part of workplace health promotion. Nowadays, the fatigue syndrome is primarily known as a side effect of cancer treatment and thus from the rehabilitation of cancer patients. Cancer-related fatigue is a massive limiting side effect for patients and the currently most effective treatment strategy against cancer-associated fatigue syndrome is physical training. The idea for this current project is, that physical exercise might have similar effects on post-SARS-CoV2 fatigue as it has on cancer-related fatigue. The current study evaluates the effects of this primarily exercise-based rehabilitation program on Long-COVID fatigue.

Publications & conference data

5 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Registered clinical trials investigating treatment of long COVID: a scoping review and recommendations for research.
    Ceban F, Leber A, Jawad MY, Yu M, et al · · 2022 · cited 52× · PMID 35282780 · DOI 10.1080/23744235.2022.2043560
  2. Exercise program for the management of anxiety and depression in adults and elderly subjects: Is it applicable to patients with post-covid-19 condition? A systematic review and meta-analysis.
    Piva T, Masotti S, Raisi A, Zerbini V, et al · · 2023 · cited 22× · PMID 36634854 · DOI 10.1016/j.jad.2022.12.155
  3. At a crossroads: coronavirus disease 2019 recovery and the risk of pulmonary vascular disease.
    Cascino TM, Desai AA, Kanthi Y. · · 2021 · cited 10× · PMID 34127622 · DOI 10.1097/mcp.0000000000000792
  4. Long COVID Symptom Management Through Self-Care and Nonprescription Treatment Options: A Narrative Review.
    Kachroo P, Boivin G, Cowling BJ, Shannon W, et al · · 2025 · PMID 41007506 · DOI 10.3390/ijerph22091362
  5. Facilitators and barriers of long-term exercise adherence in healthcare workers formerly suffering from post-COVID-19 syndrome : A qualitative 1-year follow-up and quantitative pilot study of the COFIT trial.
    Hasenöhrl T, Scharer B, Steiner M, Schmeckenbecher J, et al · · 2024 · PMID 39367278 · DOI 10.1007/s00508-024-02446-x

Verify or expand the search:

Other trials of Exercise

Trials testing the same drug.

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Currently open trials in the same condition.

Other Medical University of Vienna trials

Trials by the same sponsor.

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