Who is sponsoring NCT04841499?

NCT04841499 is sponsored by University of South Alabama.

What drugs are being tested in NCT04841499?

Interventions in NCT04841499: BASIS™ (Crystalline Nicotinamide Riboside 250mg and Pterostilbene 50mg).

Is NCT04841499 still recruiting?

NCT04841499 is currently completed. Last updated 18 November 2021.

Last reviewed 2021-11-18 · How we verify

NCT04841499

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effects of a Seven-day BASIS™ Supplementation on Menopausal Syndromes and Measurements of the Urinary Vitamin B3 and Estradiol Levels in Pre-, Peri- and Post-menopause

Completed NA Last updated 18 November 2021

What this trial tests

NA trial testing BASIS™ (Crystalline Nicotinamide Riboside 250mg and Pterostilbene 50mg) in Menopause in 40 participants. Completed in 15 July 2021.

Timeline

5 April 2021

Primary endpoint
15 July 2021

15 July 2021

Quick facts

Lead sponsor	University of South Alabama
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	40
Start date	5 April 2021
Primary completion	15 July 2021
Estimated completion	15 July 2021
Sites	1 location across United States

Drugs / interventions tested

BASIS™ (Crystalline Nicotinamide Riboside 250mg and Pterostilbene 50mg) — full drug profile →

Conditions studied

Menopause — all drugs for Menopause →

Sponsor

University of South Alabama

Who can join

35 and older, female only, with Menopause. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to determine whether a short supplementation (7days) with BASIS™ increases the natural production of estradiol, measured in urinary waste. The overall objective is to determine whether through increased estradiol levels, the undesirable menopausal effects, assessed via questionnaires, are mitigated by a short-term supplementation with BASIS™

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

New Insights into Dietary Pterostilbene: Sources, Metabolism, and Health Promotion Effects.
Nagarajan S, Mohandas S, Ganesan K, Xu B, et al · · 2022 · cited 57× · PMID 36234852 · DOI 10.3390/molecules27196316
Roles of NAD<sup>+</sup> in Health and Aging.
Lautrup S, Hou Y, Fang EF, Bohr VA. · · 2024 · cited 28× · PMID 37848251 · DOI 10.1101/cshperspect.a041193
Nicotinamide riboside and pterostilbene reduces frequency and severity of undesirable symptoms of the menopause transition: an open-label, pilot clinical trial.
Holmes HE, Srivastava K, Scalici JM, Dhuguru J, et al · · 2026 · PMID 42211736 · DOI 10.3389/fragi.2026.1773667

Verify or expand the search:

Other recruiting trials for Menopause

Currently open trials in the same condition.

NCT07472881 — Multi-Acupoint Laser Therapy for Body Shape and Composition in Obese Menopausal Women · NA · recruiting
NCT07135232 — The Effects of Resistance Training and a Plant-Based Supplement on Perimenopausal Symptoms and Muscle Health. · NA · recruiting
NCT06975111 — Focusing on the Menopausal Transition to Improve Mid-Life Women's Health · Phase 2, PHASE3 · recruiting
NCT07393672 — Effects of Hemp-Derived Cannabinoids on Menopause Symptoms · Phase 2 · recruiting
NCT07412093 — The Effect of Progressive Relaxation Exercises and Planned Education on Menopausal Symptoms, Perceived Stress, and Anxie · NA · active not recruiting

Other University of South Alabama trials

Trials by the same sponsor.

NCT06923930 — Impact of a Cueing Device on Upper Extremity Muscle Strength in Swimmers · NA · completed
NCT06467695 — Low Voltage Electrical Stimulation for Depression in Parkinson's Patients · NA · recruiting
NCT06214468 — Protective Effect of Nicotinamide Riboside Against Acetaminophen Toxicity · Phase 1 · completed
NCT05639426 — Preventing Youth Violence Through Building Equitable Communities · NA · enrolling by invitation
NCT05243563 — Does Steroid Plus CO2 Laser Improve Lichen Sclerosus Symptoms Compared to Steroids Alone? · Phase 2, PHASE3 · terminated

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04841499 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of South Alabama
Last refreshed: 18 November 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04841499.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing