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NCT04839159
Study of Biological Markers in Children With Sickle Cell Disease
NA trial testing Blood sampling in Sickle Cell Disease in 41 participants. Status unknown.
30 June 2021
Quick facts
| Lead sponsor | Queen Fabiola Children's University Hospital |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 41 |
| Start date | 10 May 2012 |
| Primary completion | 30 June 2021 |
| Estimated completion | 30 June 2021 |
| Sites | 3 locations across Belgium |
Drugs / interventions tested
- Blood sampling — full drug profile →
- Blood sampling — full drug profile →
Conditions studied
- Sickle Cell Disease — all drugs for Sickle Cell Disease →
Sponsor
Queen Fabiola Children's University Hospital
Who can join
6 Months and older, any sex, with Sickle Cell Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Sickle cell disease is associated with significant morbi-mortality hence the interest in an early and targeted care. At present, there is no plasmatic marker able to identify infants at higher risk of developping severe complications later in life. However, recent studies have demonstrated a correlation between certain complications of the disease and biomarkers of the endothelial dysfunction characterizing it. Investigators prospectively followed a cohort of children diagnosed with SCD through the universal neonatal screening using inflammatory and haemostatic plasmatic markers to study their annual evolution. Investigators then will evaluate potential associations between these biological markers and the occurrence of SCD related complications. A secondary objective of this study is to evaluate the repercussions of therapeutic intervention on these markers. .
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04839159
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Currently open trials in the same condition.
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Other Queen Fabiola Children's University Hospital trials
Trials by the same sponsor.
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- NCT04337125 — Contribution of Attachment and Educational Practices in the Expression of ADHD in School-aged Children · NA · unknown
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04839159 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Queen Fabiola Children's University Hospital
- Last refreshed: 9 April 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04839159.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing