Last reviewed · How we verify
NCT04836689
Influence of Respiratory Rate Settings on CO2 Levels During Nasal Intermittent Positive Pressure Ventilation (NIPPV).
NA trial testing nasal intermittent positive pressure ventilation (NIPPV). in Ventilator Lung; Newborn in 50 participants. Completed in 1 September 2022.
1 August 2022
Quick facts
| Lead sponsor | Rambam Health Care Campus |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | crossover |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 50 |
| Start date | 1 April 2021 |
| Primary completion | 1 August 2022 |
| Estimated completion | 1 September 2022 |
| Sites | 1 location across Israel |
Drugs / interventions tested
- nasal intermittent positive pressure ventilation (NIPPV).
Conditions studied
- Ventilator Lung; Newborn — all drugs for Ventilator Lung; Newborn →
Sponsor
Rambam Health Care Campus — full company profile →
Who can join
Under 1 Month, any sex, with Ventilator Lung; Newborn. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Infants will be monitored by TcCO2 during three consecutive time periods of one hour each on a high and low rate of NIPPV, when in a stable condition. NIPPV rate will start high/low, changed to low/high and switched back to starting rate.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The effect of changing respiratory rate settings on CO<sub>2</sub> levels during nasal intermittent positive pressure ventilation (NIPPV) in premature infants.
Hochwald O, Borenstein-Levin L, Dinur G, Jubran H, et al · · 2023 · cited 2× · PMID 36759706 · DOI 10.1038/s41372-023-01614-7
Verify or expand the search:
- PubMed search for NCT04836689
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Ventilator Lung; Newborn
Currently open trials in the same condition.
- NCT07049900 — Baby ABS (Abdominal Binder Study) · NA · recruiting
- NCT06512935 — Ventilator Pressure and Optimization of Compliance and Hemodynamics · NA · recruiting
- NCT06550219 — Evaluation of Nasal Non Invasive Ventilation in Management of Neonates With Respiratory Distress Using Lung Ultrasound · NA · recruiting
- NCT06026163 — Caffeine as an Adjuvant Therapy for Late Preterm Infants With Respiratory Distress · Phase 2, PHASE3 · recruiting
- NCT05987800 — Non-invasive Ventilation in Preterm Infants · NA · active not recruiting
Other Rambam Health Care Campus trials
Trials by the same sponsor.
- NCT07384013 — Study Protocol: Impact of Metamizole (Optalgin®) on Anti-Xa Concentrations in Oncology Patients Receiving DOACs · NA · recruiting
- NCT06688253 — Intravenous Human IgG1 Fc Fragment (Efgartigimod) in Myasthenic Crisis · Phase 4 · not yet recruiting
- NCT06235749 — Administration Of Calcium Gluconate for The Reduction of Blood Loss During Elective Cesarean Delivery · NA · recruiting
- NCT06622902 — Influence of Flow Rate Change on CO2 Levels During High Flow Nasal Ventilation (HFNV) in Preterm Infants. · NA · recruiting
- NCT05922111 — Cervical Ripening Balloon for 12 Hours vs. 1 Hour. · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04836689 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Rambam Health Care Campus
- Last refreshed: 22 September 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04836689.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing