Last reviewed · How we verify
NCT04835454
Role of Piwi-protein Interacting RNA, miRNA-194 and Amino Acids in Patients With Prostate Cancer
trial testing piRNAs, miRNA-194, regucalcin and plasma aminoacids levels in Finding New Biomarkers That Could be Evaluated in Patients With Prostate Cancer and Clarify Their Role in Early Detection of Prostate Cancer in 120 participants. Status unknown.
15 September 2021
Quick facts
| Lead sponsor | Assiut University |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 120 |
| Start date | 15 May 2021 |
| Primary completion | 15 September 2021 |
| Estimated completion | 15 December 2021 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- piRNAs, miRNA-194, regucalcin and plasma aminoacids levels
Conditions studied
- Finding New Biomarkers That Could be Evaluated in Patients With Prostate Cancer and Clarify Their Role in Early Detection of Prostate Cancer — all drugs for Finding New Biomarkers That Could be Evaluated in Patients With Prostate Cancer and Clarify Their Role in Early Detection of Prostate Cancer →
Sponsor
Assiut University
Who can join
Adults 40 to 70, male only, with Finding New Biomarkers That Could be Evaluated in Patients With Prostate Cancer and Clarify Their Role in Early Detection of Prostate Cancer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Prostate cancer is one of the most frequently diagnosed cancers and one of the main causes of death due to tumors in men . The mechanisms of its carcinogenesis have not been fully elucidated yet . Prostate tumours remain undetected or dormant for a long period of time before they progress loco-regionally or at distant sites as overt tumours. The molecular mechanism of dormancy is yet poorly understood
Publications & conference data
4 peer-reviewed publications reference this trial (live from Europe PMC):
-
Liquid Biopsy to Detect Minimal Residual Disease: Methodology and Impact.
Honoré N, Galot R, van Marcke C, Limaye N, et al · · 2021 · cited 50× · PMID 34771526 · DOI 10.3390/cancers13215364 -
MicroRNAs as clinical tools for diagnosis, prognosis, and therapy in prostate cancer.
Ghamlouche F, Yehya A, Zeid Y, Fakhereddine H, et al · · 2023 · cited 34× · PMID 36608541 · DOI 10.1016/j.tranon.2022.101613 -
Non-coding RNAs as therapeutic targets in cancer and its clinical application.
Leng X, Zhang M, Xu Y, Wang J, et al · · 2024 · cited 20× · PMID 39149142 · DOI 10.1016/j.jpha.2024.02.001 -
Targeting Regulatory Noncoding RNAs in Human Cancer: The State of the Art in Clinical Trials.
Piergentili R, Sechi S. · · 2025 · cited 2× · PMID 40284466 · DOI 10.3390/pharmaceutics17040471
Verify or expand the search:
- PubMed search for NCT04835454
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04835454 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Assiut University
- Last refreshed: 8 April 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04835454.
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