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NCT04834505

To Differentiate Focal Autoimmune Pancreatitis From Pancreatic Cancer by Endoscopic Ultrasound

Completed Last updated 31 May 2025
What this trial tests

trial testing Diagnostic imaging modalities for validation sample in Autoimmune Pancreatitis in 286 participants. Completed in 30 December 2024.

Timeline
11 May 2021
Primary endpoint
30 September 2024
30 December 2024

Quick facts

Lead sponsorPeking Union Medical College Hospital
StatusCompleted
Study typeOBSERVATIONAL
Enrollment286
Start date11 May 2021
Primary completion30 September 2024
Estimated completion30 December 2024
Sites1 location across China

Drugs / interventions tested

Conditions studied

Sponsor

Peking Union Medical College Hospital

Who can join

Under 75, any sex, with Autoimmune Pancreatitis or Pancreatic Cancer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Autoimmune pancreatitis (AIP) is a special type of chronic pancreatitis mediated by autoimmunity. The classic manifestation of AIP is diffuse pancreatic enlargement, some of which are characterized by focal enlargement. Clinically, it is divided into diffuse AIP (DAIP) and focal AIP (FAIP) according to morphology. FAIP can be clinically manifested as obstructive jaundice, peripancreatic lymphadenopathy and vascular involvement, which may mimic pancreatic cancer (PC). CT/MRI is the important imaging tool for diagnosing pancreatic diseases. However, due to the overlap of the imaging features of FAIP and PC, it is challenging to differentiate the two by CT/MRI. Endoscopic ultrasound (EUS) can clearly display the pancreatic parenchyma and pancreatic duct system and has become a routine modality for the evaluation of pancreatic diseases. The aim of this study is to construct a diagnosis model for distinguishing between FAIP and PC by comparing the EUS characteristics of the two, and further validate its diagnostic efficacy.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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Other recruiting trials for Autoimmune Pancreatitis

Currently open trials in the same condition.

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Data sources for this page

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