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NCT04834050
Can 4 Weeks of Exercise Program Change Quadriceps Architecture in Patients With Rheumatoid Arthritis
NA trial testing Quadriceps femoris isometric home-based exercise in Arthritis, Rheumatoid in 37 participants. Completed in 20 February 2020.
12 June 2019
Quick facts
| Lead sponsor | Ovgu Bickici |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 37 |
| Start date | 1 October 2018 |
| Primary completion | 12 June 2019 |
| Estimated completion | 20 February 2020 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Quadriceps femoris isometric home-based exercise
Conditions studied
- Arthritis, Rheumatoid — all drugs for Arthritis, Rheumatoid →
- Knee Osteoarthritis — all drugs for Knee Osteoarthritis →
- Quadriceps Muscle Atrophy — all drugs for Quadriceps Muscle Atrophy →
- Ultrasonography — all drugs for Ultrasonography →
Sponsor
Ovgu Bickici
Who can join
Adults 18 to 65, any sex, with Arthritis, Rheumatoid or Knee Osteoarthritis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Quadriceps femoris (QF) atrophy is seen in rheumatoid arthritis and knee osteoarthritis (OA) patients. Exercise therapy is mile stone in knee OA patients also it can help thicken QF muscle of RA patients. We primarily aimed to demonstrate the influence of 4 weeks of knee isometric home-based training on QF muscle parts thickness and pennation angle measurements of RA patients with ultrasonography (USG). This study included 12 patients with RA, 12 patients with knee OA as positive control group and 13 volunteers as healthy control group. All participants were given 4 weeks of quadriceps-hamstring isometric home-based training. At baseline and at the end of the program, WOMAC and Lequesne algofunctional index scores of knee OA patients and DAS28-CRP scores of RA patients were recorded. Dominant knee thickness and pennation angle measurements of QF muscle parts were evaluated by ultrasonography.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04834050
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04834050 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ovgu Bickici
- Last refreshed: 6 April 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04834050.
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