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NCT04832945

SARS-CoV-2 Pre-exposure Prophylaxis With Ivermectin Retrospective Cohort Study

Completed Last updated 13 April 2021
What this trial tests

trial testing Ivermectin 6 Mg Oral Tablet in Covid19 in 713 participants. Completed in 10 April 2021.

Timeline
29 June 2020
Primary endpoint
20 September 2020
10 April 2021

Quick facts

Lead sponsorGrupo Rescue S.A.S República Dominicana
StatusCompleted
Study typeOBSERVATIONAL
Enrollment713
Start date29 June 2020
Primary completion20 September 2020
Estimated completion10 April 2021
Sites2 locations across Dominican Republic

Drugs / interventions tested

Conditions studied

Sponsor

Grupo Rescue S.A.S República Dominicana

Who can join

18 and older, any sex, with Covid19. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This observational study, a multicenter retrospective cohort database study, carried out in two medical centers, Centro Medico Bournigal (CMBO) in Puerto Plata and Centro Medico Punta Cana (CMPC) in Punta Cana, Dominican Republic, sought to determine whether Ivermectin, at a weekly orally dose of 0.2 mg/kg, is an effective pre-exposure prophylactic method (PrEP) for the spread of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), in the healthcare workers. The study began on June 29, 2020 and ended on July 26, 2020 (4 weeks).

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Potential Prophylactic Treatments for COVID-19.
    Ben-Zuk N, Dechtman ID, Henn I, Weiss L, et al · · 2021 · cited 9× · PMID 34372498 · DOI 10.3390/v13071292
  2. Ivermectin as a SARS-CoV-2 Pre-Exposure Prophylaxis Method in Healthcare Workers: A Propensity Score-Matched Retrospective Cohort Study.
    Morgenstern J, Redondo JN, Olavarria A, Rondon I, et al · · 2021 · cited 8× · PMID 34513523 · DOI 10.7759/cureus.17455
  3. Retrospective cohort study of Ivermectin as a SARS-CoV-2 pre-exposure prophylaxis method in Healthcare Workers
    Morgenstern J, Redondo JN, Olavarría Á, Rondon I, et al · · 2021 · cited 1× · DOI 10.1101/2021.04.10.21255248

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04832945.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing