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NCT04832945
SARS-CoV-2 Pre-exposure Prophylaxis With Ivermectin Retrospective Cohort Study
trial testing Ivermectin 6 Mg Oral Tablet in Covid19 in 713 participants. Completed in 10 April 2021.
20 September 2020
Quick facts
| Lead sponsor | Grupo Rescue S.A.S República Dominicana |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 713 |
| Start date | 29 June 2020 |
| Primary completion | 20 September 2020 |
| Estimated completion | 10 April 2021 |
| Sites | 2 locations across Dominican Republic |
Drugs / interventions tested
- Ivermectin 6 Mg Oral Tablet — full drug profile →
Conditions studied
- Covid19 — all drugs for Covid19 →
Sponsor
Grupo Rescue S.A.S República Dominicana
Who can join
18 and older, any sex, with Covid19. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This observational study, a multicenter retrospective cohort database study, carried out in two medical centers, Centro Medico Bournigal (CMBO) in Puerto Plata and Centro Medico Punta Cana (CMPC) in Punta Cana, Dominican Republic, sought to determine whether Ivermectin, at a weekly orally dose of 0.2 mg/kg, is an effective pre-exposure prophylactic method (PrEP) for the spread of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), in the healthcare workers. The study began on June 29, 2020 and ended on July 26, 2020 (4 weeks).
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Potential Prophylactic Treatments for COVID-19.
Ben-Zuk N, Dechtman ID, Henn I, Weiss L, et al · · 2021 · cited 9× · PMID 34372498 · DOI 10.3390/v13071292 -
Ivermectin as a SARS-CoV-2 Pre-Exposure Prophylaxis Method in Healthcare Workers: A Propensity Score-Matched Retrospective Cohort Study.
Morgenstern J, Redondo JN, Olavarria A, Rondon I, et al · · 2021 · cited 8× · PMID 34513523 · DOI 10.7759/cureus.17455 -
Retrospective cohort study of Ivermectin as a SARS-CoV-2 pre-exposure prophylaxis method in Healthcare Workers
Morgenstern J, Redondo JN, Olavarría Á, Rondon I, et al · · 2021 · cited 1× · DOI 10.1101/2021.04.10.21255248
Verify or expand the search:
- PubMed search for NCT04832945
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Ivermectin 6 Mg Oral Tablet
Trials testing the same drug.
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Other recruiting trials for Covid19
Currently open trials in the same condition.
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- NCT04924803 — Community Developed Technology-Based Messaging to Increase COVID-19 Vaccine Uptake Among People Who Inject Drugs · NA · active not recruiting
- NCT05013632 — COVID-19 International Drug Pregnancy Registry · recruiting
- NCT04806061 — Urine Alkalinisation in COVID-19 · NA · active not recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04832945 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Grupo Rescue S.A.S República Dominicana
- Last refreshed: 13 April 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04832945.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing