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NCT04831346
Effects of Low-Level Laser Therapy on Mouth Opening and Surface Electromyography in Temporomandibular Disorders
NA trial testing Low level laser in Temporomandibular Joint Dysfunction Syndrome in 100 participants. Currently enrolling.
1 December 2024
Quick facts
| Lead sponsor | Cairo University |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 100 |
| Start date | 1 November 2020 |
| Primary completion | 1 December 2024 |
| Estimated completion | 1 February 2025 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Low level laser
- Soft occlusive splint
Conditions studied
- Temporomandibular Joint Dysfunction Syndrome — all drugs for Temporomandibular Joint Dysfunction Syndrome →
- Pain, Face — all drugs for Pain, Face →
Sponsor
Cairo University
Who can join
Adults 18 to 30, female only, with Temporomandibular Joint Dysfunction Syndrome or Pain, Face. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is a one year followup study that aims to assess the efficacy of low level laser therapy (LLLT) on pain, mouth opening and masticatory muscle activity in cases of temporomandibular dysfunction (TMD) as compared to soft occlusive splints.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Occlusal interventions for managing temporomandibular disorders.
Singh BP, Singh N, Jayaraman S, Kirubakaran R, et al · · 2024 · cited 22× · PMID 39282765 · DOI 10.1002/14651858.cd012850.pub2 -
Effects of low-level laser therapy versus soft occlusive splints on mouth opening and surface electromyography in females with temporomandibular dysfunction: A randomized-controlled study.
Shousha T, Alayat M, Moustafa I. · · 2021 · cited 19× · PMID 34597318 · DOI 10.1371/journal.pone.0258063
Verify or expand the search:
- PubMed search for NCT04831346
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Low level laser
Trials testing the same drug.
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- NCT06493721 — Clear Aligner Treatment With and Without Low Level Laser Therapy for Upper Incisor Crowding · NA · completed
- NCT03239912 — Treatment of Class II Malocclusion Combined With Low-level Laser · NA · completed
Other recruiting trials for Temporomandibular Joint Dysfunction Syndrome
Currently open trials in the same condition.
- NCT06148818 — Effect of Progressive Neck Motor Control Exercises on Temporomandibular Joint Dysfunction · NA · recruiting
- NCT06661096 — Comparative Study Between Level I and Level II Temporomandibular Joint Arthroscopy in Wilkes Stage III Patients · NA · active not recruiting
- NCT05006963 — Tele-Rehabilitation in Patients With Temporomandibular Dysfunction · NA · recruiting
Other Cairo University trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04831346 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Cairo University
- Last refreshed: 21 August 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04831346.
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