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NCT04828421
The Effect of Probiotic Supplementation on Cognitive and Emotional Functions in Healthy Elderly Subjects
NA trial testing Lactobacillus rhamnosus and Bifidobacterium lactis in Healthy in 36 participants. Completed in 30 April 2022.
30 April 2022
Quick facts
| Lead sponsor | Universidad de Almeria |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | triple |
| Primary purpose | prevention |
| Enrollment | 36 |
| Start date | 17 July 2020 |
| Primary completion | 30 April 2022 |
| Estimated completion | 30 April 2022 |
| Sites | 3 locations across Spain |
Drugs / interventions tested
- Lactobacillus rhamnosus and Bifidobacterium lactis
- Placebo
Conditions studied
- Healthy — all drugs for Healthy →
Sponsor
Universidad de Almeria
Who can join
56 and older, any sex, with Healthy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study evaluates the cognitive and emotional effects of probiotics in healthy elderly patients.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Cognitive and Emotional Effect of a Multi-species Probiotic Containing Lactobacillus rhamnosus and Bifidobacterium lactis in Healthy Older Adults: A Double-Blind Randomized Placebo-Controlled Crossover Trial.
Ruiz-Gonzalez C, Cardona D, Rueda-Ruzafa L, Rodriguez-Arrastia M, et al · · 2025 · cited 12× · PMID 38935259 · DOI 10.1007/s12602-024-10315-2
Verify or expand the search:
- PubMed search for NCT04828421
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Universidad de Almeria trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04828421 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Universidad de Almeria
- Last refreshed: 1 June 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04828421.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing