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NCT04823988
Emotional, Social, Cognitive and Behavioral Sequalae of the COVID-19 Pandemic
trial in Healthy Volunteer in 2,086 participants. Completed in 26 April 2023.
1 May 2022
Quick facts
| Lead sponsor | National Institute of Mental Health (NIMH) |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 2,086 |
| Start date | 13 April 2021 |
| Primary completion | 1 May 2022 |
| Estimated completion | 26 April 2023 |
| Sites | 1 location across United States |
Conditions studied
- Healthy Volunteer — all drugs for Healthy Volunteer →
Sponsor
National Institute of Mental Health (NIMH)
Who can join
Adults 18 to 99, any sex, with Healthy Volunteer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Background: COVID-19 has caused a high rate of deaths. The steps taken to control its spread have caused social isolation, changes in lifestyle, economic turmoil, and increased work-related stress. As a result, there has been a rise in mental and physical health problems. These burdens are particularly severe for people with a history of mental illness. Researchers want to learn more about the relationship between stressors related to COVID-19 and self-rated measures of anxiety and other variables. Objective: To better understand the impact of this stressful time on people s lives and families. Also, to learn the strategies people have been using to deal with the COVID-19 pandemic. Eligibility: Adults ages 18 and older. Design: This is an online study. Participants will fill out surveys online. The surveys will ask about their mood, anxiety, medical history, substance use, and COVID-19 stressors. Participants will complete an online task. For the task, they will stare at the center of a computer screen. When they see certain images, they will indicate the location of that image as quickly as possible. It will take about 1.5 hours for participants to complete the surveys and tasks. They may be contacted again if additional data is needed. Some participants may have taken part in other NIH studies. If so, their new data may be linked to their previously collected data.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The Impact of Government Lockdowns on the Mental Health of the General Population: A Systematic Review and Meta-analysis.
Okazaki Y, Tsujimoto Y, Yamada K, Saka N, et al · · 2025 · PMID 40453305 · DOI 10.7759/cureus.83249
Verify or expand the search:
- PubMed search for NCT04823988
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other National Institute of Mental Health (NIMH) trials
Trials by the same sponsor.
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- NCT06874205 — Assessment of 11C-JMJ-129 for Imaging PDE4D in Brain and Whole Body of Healthy Volunteers · Phase 1 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04823988 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Institute of Mental Health (NIMH)
- Last refreshed: 31 May 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04823988.
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