Last reviewed · How we verify
NCT04822480
Evaluation of a Telehealth DPP With Medicare Patients at the University of Mississippi Medical Center
trial testing Diabetes Prevention Program (DPP) in PreDiabetes in 500 participants. Participants enrolled and being followed up; not accepting new ones.
31 December 2023
Quick facts
| Lead sponsor | University of Mississippi Medical Center |
|---|---|
| Status | Active, enrolled |
| Study type | OBSERVATIONAL |
| Enrollment | 500 |
| Start date | 1 February 2020 |
| Primary completion | 31 December 2023 |
| Estimated completion | 31 December 2024 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Diabetes Prevention Program (DPP)
Conditions studied
- PreDiabetes — all drugs for PreDiabetes →
- Prediabetic State — all drugs for Prediabetic State →
Sponsor
University of Mississippi Medical Center
Who can join
18 and older, any sex, with PreDiabetes or Prediabetic State. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The National Diabetes Prevention Program (DPP) is an evidence-based, 12-month lifestyle change program to prevent or delay the onset of type 2 diabetes mellitus (herein referred to as 'diabetes') among adults with prediabetes. The Department of Preventive Medicine, University of Mississippi Medical Center (UMMC), in partnership with the American Medical Association, is collaborating to develop and implement the DPP as a clinical service for UMMC patients beginning in September 2020. We aim to recruit 245 patients per year over 3 years. Because this is the first attempt to develop and implement the DPP as a clinical service at the UMMC, we are proposing to conduct a comprehensive process, outcome, impact and return on investment evaluation. An effectiveness-implementation hybrid research design will be used to (1) evaluate a multifaceted implementation strategy and the effectiveness and impact of the DPP delivered using telehealth by UMMC's Department of Preventive Medicine; (2) conduct an analysis on medical expenditures among those who participate in a DPP to measure net savings and return on investment (ROI) relative to non-participants; (3) conduct a longitudinal cohort analysis to assess incidence of diabetes and changes in body composition, biomarkers, and psycho-social behavioral constructs among those who participate in a DPP relative to those who do not. The findings from this comprehensive research evaluation will be used to (1) improve clinical operations and implementation; (2) demonstrate the cost benefit of the DPP as a clinical service for patients with diabetes risk; and (3) provide empirical support for delivering the DPP via different modalities including telehealth to reduce risk and improve health outcomes among patients.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Telehealth Diabetes Prevention Program for Adults With Prediabetes in an Academic Medical Center Setting: Protocol for a Hybrid Type III Trial.
Gamble A, Khan T, Hughes A, Guo Y, et al · · 2023 · PMID 37955955 · DOI 10.2196/50183
Verify or expand the search:
- PubMed search for NCT04822480
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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- NCT07220057 — Sustainable Culturally Adapted Nutrition (SCAN) Program · NA · completed
Other recruiting trials for PreDiabetes
Currently open trials in the same condition.
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Other University of Mississippi Medical Center trials
Trials by the same sponsor.
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- NCT06216925 — Teen Mom Study: A Confirmatory Pragmatic Cluster RCT · NA · not yet recruiting
- NCT06973642 — Evaluation of Home-based Telerehabilitation Platform to Augment Orthopedic Rehabilitation · NA · recruiting
- NCT07071064 — Mississippi Community Engagement Alliance (MS CEAL): Fostering Community Solutions · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04822480 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Mississippi Medical Center
- Last refreshed: 29 April 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04822480.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing