NCT04821193

Comparison of the Effects of 5%NaHCO3, 2%CHG and 70%Alcohol in the Prevention of Infections Related to Catheter

Completed NA Last updated 29 March 2021

What this trial tests

NA trial testing Skin antisepsis with 5% NaHCO3 water solution in Disinfectant Dye Adverse Reaction in 62 participants. Completed in 27 July 2020.

Timeline

7 November 2017

Primary endpoint
27 July 2020

27 July 2020

Quick facts

Lead sponsor	Istanbul University - Cerrahpasa
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	prevention
Enrollment	62
Start date	7 November 2017
Primary completion	27 July 2020
Estimated completion	27 July 2020
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

• Skin antisepsis with 5% NaHCO3 water solution — full drug profile →
• Skin antisepsis with 2% Chlorhexidine Gluconate solution — full drug profile →

Conditions studied

• Disinfectant Dye Adverse Reaction — all drugs for Disinfectant Dye Adverse Reaction →
• Catheter-Related Infections — all drugs for Catheter-Related Infections →
• Nursing Caries — all drugs for Nursing Caries →
• Children, Only — all drugs for Children, Only →

Sponsor

Istanbul University - Cerrahpasa

Who can join

Adults 1 to 18, any sex, with Disinfectant Dye Adverse Reaction or Catheter-Related Infections. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Intravenous catheters have become one of the indispensable tools of modern medicine. Peripheric intravenous catheters facilitate the work of healthcare professionals in the treatment phase, especially in diagnostic procedures. Intravenous catheters cause microorganisms to enter the bloodstream by damaging the skin, which is the body's first defense barrier. In this case, it causes infections, sepsis, an increase in mortality and morbidity rates, prolongation of hospital stay, increase in antibiotic use, and medical expenses. The density of the skin flora in the area where the catheter will be inserted is a major risk factor for infection.To prevent complications associated with peripheric intravenous catheters; Performing the procedure in line with the principles of surgical asepsis and following the correct follow-up are among the most important measures that the nurse should take. Also, the child and the parents should be prepared for the procedure and the appropriate environment should be provided. Along with correct catheter placement and care, antisepsis of the cannula placement area is among the indicators of nursing care.

As well as the effectiveness and safety of skin disinfectants, topical absorption, lack of toxic effect, local and irritation effect are also important. Solutions with 5% NaHCO3 have recently come to the fore as antiseptic agents. When the literature is examined, it has not been found that there are very few studies on this solution and it is used in skin antisepsis before peripheral intravenous catheterization in children. This study was planned as a randomized controlled experimental design to determine the effectiveness of 5% NaHCO3 water solution in catheter site cleaning in pediatric patients by comparing it with the most commonly used antiseptic agents and to monitor the development of catheter-related infections.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.