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NCT04818502: RESOLVE-MR
Real World Study of the Tendyne™ Mitral Valve System to Treat Mitral Regurgitation
trial testing Tendyne™ Mitral Valve System in Mitral Valve Regurgitation in 200 participants. Participants enrolled and being followed up; not accepting new ones.
31 May 2025
Quick facts
| Lead sponsor | Abbott Medical Devices |
|---|---|
| Status | Active, enrolled |
| Study type | OBSERVATIONAL |
| Enrollment | 200 |
| Start date | 4 May 2021 |
| Primary completion | 31 May 2025 |
| Estimated completion | 31 May 2029 |
| Sites | 36 locations across France, Italy, Netherlands, Belgium, Austria, Saudi Arabia, United Kingdom, Germany |
Drugs / interventions tested
- Tendyne™ Mitral Valve System
Conditions studied
- Mitral Valve Regurgitation — all drugs for Mitral Valve Regurgitation →
Sponsor
Abbott Medical Devices — full company profile →
Who can join
18 and older, any sex, with Mitral Valve Regurgitation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To evaluate the safety and performance of the Tendyne™ Mitral Valve System when used as intended in a contemporary, real-world setting.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Transcatheter Mitral Valve Replacement Using Transcatheter Aortic Valve or Dedicated Devices: Current Evidence and Future Prospects.
Quentin V, Mesnier J, Delhomme C, Sayah N, et al · · 2023 · cited 8× · PMID 37959178 · DOI 10.3390/jcm12216712
Verify or expand the search:
- PubMed search for NCT04818502
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Mitral Valve Regurgitation
Currently open trials in the same condition.
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- NCT04577248 — The Prospecive OBSERVational Munich Interventional MITRAl-Valve Registry · recruiting
Other Abbott Medical Devices trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04818502 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Abbott Medical Devices
- Last refreshed: 12 June 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04818502.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing