NCT04818450 (GASWAC) is a NA clinical trial of Gabapentin in Sleep Deprivation, sponsored by Mahidol University.

Who is sponsoring NCT04818450?

NCT04818450 is sponsored by Mahidol University.

What drugs are being tested in NCT04818450?

Interventions in NCT04818450: Gabapentin.

What condition does NCT04818450 study?

NCT04818450 studies Sleep Deprivation, Critically Ill.

Is NCT04818450 still recruiting?

NCT04818450 is currently completed. Last updated 11 August 2022.

Last reviewed 2022-08-11 · How we verify

NCT04818450: GASWAC

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Impact of Gabapentin on Slow Wave Sleep in Adult Critically Ill Patient

Completed NA Last updated 11 August 2022

What this trial tests

NA trial testing Gabapentin in Sleep Deprivation in 60 participants. Completed in 31 July 2022.

Timeline

19 April 2021

Primary endpoint
25 June 2022

31 July 2022

Quick facts

Lead sponsor	Mahidol University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	prevention
Enrollment	60
Start date	19 April 2021
Primary completion	25 June 2022
Estimated completion	31 July 2022
Sites	1 location across Thailand

Drugs / interventions tested

Gabapentin (Gabapentin) — full drug profile →

Conditions studied

Sleep Deprivation — all drugs for Sleep Deprivation →
Critically Ill — all drugs for Critically Ill →

Sponsor

Mahidol University

Who can join

18 and older, any sex, with Sleep Deprivation or Critically Ill. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The investigators proposed that gabapentin will increase slow-wave sleep in adult critically ill patients. Increasing slow-wave sleep will improve the patients' outcomes (shortening ICU length of stay, improving ventilator free days, increasing delirium free days) in critically ill patients, a university hospital, Thailand.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Effects of gabapentin on slow-wave sleep period in critically ill adult patients: A randomized controlled trial.
Susantitapong K, Dilokpattanamongkol P, Sutherasan Y, Liamsombut S, et al · · 2024 · cited 3× · PMID 38803031 · DOI 10.1111/cts.13815
Effects of gabapentin on slow-wave sleep period in critically ill adult patients: a randomized controlled trial
Susantitapong K, Sutherasan Y, Liamsombut S, Dilokpattanamongkol P, et al · · 2023 · DOI 10.21203/rs.3.rs-2586319/v1

Verify or expand the search:

Other trials of Gabapentin

Trials testing the same drug.

NCT07047040 — Analgesic Efficacy of Pre-operative Dose of Ketorolac and Gabapentin · Phase 2, PHASE3 · not yet recruiting
NCT07131527 — Comparison Between Oral Gabapentin Versus Diclofenac Sodium in Post-operative Analgesia Laparoscopic Cholecystectomy · NA · recruiting
NCT04613024 — Beneficial Side Effects of Topiramate in Obese Patients Undergoing Total Joint Arthroplasty · EARLY_PHASE1 · withdrawn
NCT07389551 — Comparison of Pregabalin Versus Gabapentin as Pre-emptive Analgesic · NA · completed
NCT06992427 — High-dose Prophylactic Gabapentin (HOPE) vs. Placebo to Prevent Opioid Use for Oral Mucositis Pain During Concurrent Che · Phase 3 · recruiting

Other recruiting trials for Sleep Deprivation

Currently open trials in the same condition.

NCT07438912 — Mind After Midnight · NA · recruiting
NCT07329283 — Nighttime Synchrony of Your Nutrition and Circadian Health · NA · recruiting
NCT07294781 — Circadian Rhythms and Time Perception in Healthy Adults During Constant Wakefulness · NA · recruiting
NCT07085754 — Effects of Acute Sleep Deprivation on Individuals With Different APOE Genotypes · NA · recruiting
NCT06492109 — The Peripheral Blood Multi-Omics Study on Sleep Loss · NA · recruiting

Other Mahidol University trials

Trials by the same sponsor.

NCT07568496 — Greater Occipital Nerve Block for Migraine With Medication Overuse Headache · NA · not yet recruiting
NCT07407400 — Lemborexant for Sleep and Delirium Prevention in Elderly ICU Patients · Phase 4 · not yet recruiting
NCT07378501 — Thai Version of the Pediatric Quality of Recovery Score (PedSQoR): Translation and Psychometric Validation Study · not yet recruiting
NCT07438301 — Septic Shock Hemodynamic Respond to Volume Resuscitation Versus Vasopressor Administration · not yet recruiting
NCT07390006 — Enabling Patient-Reported Outcomes Through Innovative Care - ACS (EPIC-ACS) · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04818450 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Mahidol University
Last refreshed: 11 August 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04818450.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing