Sedation Complications in Urology During Spinal Anesthesia With Dexmedetomidine or Midazolam Regarding OSA Risk

NCT04817033 PHASE4 COMPLETED

Light to moderate sedation is recommended during surgery with spinal anesthesia . This study is exploring which sedation drug is better, midazolam or dexmedetomidine for transurethral resection of bladder and prostate in patients with or without high risk for obstructive sleep apnea (OSA). Patients were divided in two groups regarding OSA risk, and each group received midazolam or dexmedetomidine for sedation. Investigators observed intraoperative complications of airway and factors that are disturbing surgeon(movement due to participants coughing and restlessness) because one could puncture bladder or prostate and cause perforation.

Details

Lead sponsor	University Hospital of Split
Phase	PHASE4
Status	COMPLETED
Enrolment	115
Start date	Thu Apr 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Tue Feb 01 2022 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

• Anesthesia
• Anesthesia Complication
• Osa Syndrome
• Transurethral Resection of Prostate
• Sedation Complication
• Intraoperative Complications
• Snoring
• Airway Obstruction

Interventions

• Spinal anesthesia with intraoperative dexmedetomidine sedation
• Spinal anesthesia with intraoperative midazolam sedation
• Dexmedetomidine
• Midazolam

Countries

Croatia