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NCT04816851
Aortic Valve Leaflets Reconstruction (Ozaki Procedure) in Aortic Valve Diseases
trial testing OZAKI technique in Aortic Valve Disease in 1 participant. Completed in 30 July 2023.
30 June 2023
Quick facts
| Lead sponsor | Assiut University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 1 |
| Start date | 30 March 2021 |
| Primary completion | 30 June 2023 |
| Estimated completion | 30 July 2023 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- OZAKI technique
Conditions studied
- Aortic Valve Disease — all drugs for Aortic Valve Disease →
Sponsor
Assiut University
Who can join
Eligibility, any sex, with Aortic Valve Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Prospective Cohort Study aims at elaborating the outcomes of the Tricuspid Reconstruction of Aortic valve leaflets using autologous pericardium (Ozaki procedure) in the adult and paediatric patients. A very promising technique with the potential benefits of dodging oral anticoagulation, foreign material, and suitable for patients with small aortic annuli and in infectious endocarditis. Performing hemodynamic evaluation, assess the clinical implementation and report preliminary results at follow up .
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Egyptian experience with aortic valve repair using Ozaki procedure in adult and pediatric patients.
Omar MEE, Mahmoud GM, Fadaly A, Azzam M, et al · · 2025 · PMID 40221800 · DOI 10.1186/s13019-025-03351-8
Verify or expand the search:
- PubMed search for NCT04816851
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04816851 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Assiut University
- Last refreshed: 20 January 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04816851.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing