65 and older, any sex, with Fall or Risk Reduction. Patients with the condition only — healthy volunteers not accepted.
Results — posted to ClinicalTrials.gov
Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.
Number of Participants With Reported FallsPrimary· 7 months
Record of falls in prior year, and between each subsequent visit.
Baseline (All Participants)
Group
Value
95% CI
HOP-UP-PT Program
37
Normal Level of Activity
34
Baseline (Moderat and High STEADI Risk)
Group
Value
95% CI
HOP-UP-PT Program
29
Normal Level of Activity
24
3 Month (All Participants)
Group
Value
95% CI
HOP-UP-PT Program
5
Normal Level of Activity
3
3 Month (Moderate and Hight STEADI Risk)
Group
Value
95% CI
HOP-UP-PT Program
5
Normal Level of Activity
2
7 months (All Participants)
Group
Value
95% CI
HOP-UP-PT Program
7
Normal Level of Activity
15
7 Month (Moderate and High STEADI Risk)
Group
Value
95% CI
HOP-UP-PT Program
1
Normal Level of Activity
11
Modified Short Physical Performance Battery (SPPB)Primary· 7 Months
The Modified SPPB uses a 0-12 scale (0 = lowest function, 12 = highest function), calculated using collective outcomes of The Four Test Balance Scale (0= unable to perform, 1 = able to stand: feet together \>10 sec, 2 = semi-tandem \>10 sec, 4 = tandem stance \>10 sec, higher score is better balance), 5 Time Sit to Stand (0 = \>60 sec, 1=16.7 to 60 sec, 2 = 13.7 to 16.69 sec, 3 = 11.2 to 13.69 sec, and 4 = \<11.19 sec, faster time is higher function), and the 3-meter gait speed test (0 = unable to perform, 1= \> 6.52 sec, 2 = 4.66 to 6.52 sec, 3 = 3.62 to 4.65 sec, and 4 = \< 3.62 sec, faster
Baseline (all participants)
Group
Value
95% CI
HOP-UP-PT Program
8.44
± 2.66
Normal Level of Activity
7.34
± 2.85
Baseline (Moderate and high STEADI Risk)
Group
Value
95% CI
HOP-UP-PT Program
7.64
± 2.82
Normal Level of Activity
6.18
± 2.86
3 Month (all participants)
Group
Value
95% CI
HOP-UP-PT Program
9.29
± 2.49
Normal Level of Activity
8.04
± 2.97
3 Month (Moderate and High STEADI Risk)
Group
Value
95% CI
HOP-UP-PT Program
8.24
± 2.43
Normal Level of Activity
6.60
± 2.95
7 Month (all participants)
Group
Value
95% CI
HOP-UP-PT Program
9.50
± 2.22
Normal Level of Activity
8.96
± 2.63
7 Month (Moderate and High STEADI Risk)
Group
Value
95% CI
HOP-UP-PT Program
7.64
± 2.17
Normal Level of Activity
7.25
± 2.67
Timed Up and GoPrimary· 7 Months
The Timed Up and Go (TUG) is a times assessment of sit to stand transfer, 20 foot bought of ambulation with a 180 degree turn at 10 feet concluding with a stand to sit transfer.
Baseline (All participants)
Group
Value
95% CI
HOP-UP-PT Program
11.5
± 4.6
Normal Level of Activity
13.3
± 6.0
Baseline (Moderate and High STEADI Risk)
Group
Value
95% CI
HOP-UP-PT Program
12.9
± 5.3
Normal Level of Activity
15.7
± 6.8
3 Month (All participants)
Group
Value
95% CI
HOP-UP-PT Program
10.7
± 3.7
Normal Level of Activity
13.0
± 6.3
3 Month (Moderate and High STEADI Risk)
Group
Value
95% CI
HOP-UP-PT Program
12.0
± 4.3
Normal Level of Activity
15.4
± 7.5
7 Month (All participants)
Group
Value
95% CI
HOP-UP-PT Program
10.6
± 3.7
Normal Level of Activity
11.9
± 5.4
7 Month (Moderate and High STEADI Risk)
Group
Value
95% CI
HOP-UP-PT Program
13.8
± 4.3
Normal Level of Activity
14.6
± 6.8
Stopping Elderly Accidents, Death & Injuries (STEADI) Fall Risk CategorizationPrimary· 7 Months
Low, moderate, and high risk was determined relative to results of the stay independent brochure, subjective report of falls and fall risk and brochure questions, as well as gait, strength, and balance assessment. The Stopping Elderly Accidents, Death \& Injuries (STEADI) Algorithm underwent revisions since the study onset, the 2015 version was utilized as a guide for key outcome metrics reported in this study. Low STEADI risk =0, moderate STEADI risk =1, and high STEADI risk = 2. Low risk participants were categorized based on "no" responses to falls or fall risk questions as well as no gait,
Baseline (All participants)
Group
Value
95% CI
HOP-UP-PT Program
0.8
± 0.7
Normal Level of Activity
0.7
± 0.7
3 Month (All participants)
Group
Value
95% CI
HOP-UP-PT Program
0.6
± 0.7
Normal Level of Activity
0.7
± 0.6
7 Month (All Participants)
Group
Value
95% CI
HOP-UP-PT Program
0.4
± 0.6
Normal Level of Activity
0.6
± 0.7
Stay Independent QuestionnaireSecondary· 3 Months
This questionnaire scores a fall risk on a scale from zero to 14, with 4 or more indicating a possible fall risk. Zero is the lowest fall risk score, 14 is a highest fall risk score.
Baseline (All participants)
Group
Value
95% CI
HOP-UP-PT Program
4.8
± 3.0
Normal Level of Activity
4.7
± 3.2
Baseline (Moderate and High STEADI Risk)
Group
Value
95% CI
HOP-UP-PT Program
6.4
± 2.7
Normal Level of Activity
6.2
± 2.5
3 Months (All participants)
Group
Value
95% CI
HOP-UP-PT Program
3.3
± 2.9
Normal Level of Activity
4.2
± 2.8
3 Month (Moderate and High STEADI Risk)
Group
Value
95% CI
HOP-UP-PT Program
5.0
± 3.0
Normal Level of Activity
5.2
± 2.6
Modified Falls Efficacy ScaleSecondary· 3 Months
Measures fear of falling for 10 indoor and 4 outdoor activities. For each statement the participant circles a number that corresponds to their level of confidence, with zero being no confidence and 10 being extreme confidence. Once all 14 items are scored, they are added for a total score maximum of 140 which is then divided by 14. A number closer to 14 equates to more confidence, and a number closer to zero equates to less confidence.
Baseline (All participants)
Group
Value
95% CI
HOP-UP-PT Program
9.2
± 1.7
Normal Level of Activity
9.0
± 1.8
Baseline (Moderate and High STEADI Risk)
Group
Value
95% CI
HOP-UP-PT Program
8.6
± 1.8
Normal Level of Activity
8.4
± 2.3
3 Month (All participants)
Group
Value
95% CI
HOP-UP-PT Program
9.7
± 1.1
Normal Level of Activity
9.2
± 1.7
3 Month (Moderate and High STEADI Risk)
Group
Value
95% CI
HOP-UP-PT Program
9.6
± 1.2
Normal Level of Activity
8.7
± 2.1
Health Behavior QuestionnaireSecondary· 3 Months
Assessment of current behaviors related to physical activity, consuming fruits and vegetables, not smoking, and being at a recommended weight. Patients are categorized using the five levels of the trans-theoretical model of behavior change. The pre-contemplating stage, or not ready for change is scored a 5. The contemplation stage or considering making a change in the next 6 months is scored a four. The preparation or preparing to make the change in the next 6 months is scored a 3. The action stage indicates the participant has made the change and is scored. The maintenance stage indicates the
Baseline (All participants) Physical Activity
Group
Value
95% CI
HOP-UP-PT Program
2.0
± 1.2
Normal Level of Activity
1.9
± 1.3
Baseline (All participants) Fruit and Vegetable Consumption
Group
Value
95% CI
HOP-UP-PT Program
2.2
± 1.3
Normal Level of Activity
2.4
± 1.5
Baseline (All participants) Smoking Habits
Group
Value
95% CI
HOP-UP-PT Program
1.1
± 0.5
Normal Level of Activity
1.1
± .04
Baseline (All participants) Recommended Weight
Group
Value
95% CI
HOP-UP-PT Program
2.2
± 1.3
Normal Level of Activity
2.2
± 1.5
3 Month (All participants) Physical Activity
Group
Value
95% CI
HOP-UP-PT Program
1.7
± 1.0
Normal Level of Activity
2.2
± 1.5
3 Month (All participants) Fruit and Vegetable
Group
Value
95% CI
HOP-UP-PT Program
2.0
± 1.2
Normal Level of Activity
2.2
± 1.5
3 Month (All participants) Smoking
Group
Value
95% CI
HOP-UP-PT Program
1.0
± 0.3
Normal Level of Activity
1.1
± 0.4
3 Month (All participants) Recommended Weight
Group
Value
95% CI
HOP-UP-PT Program
1.9
± 1.2
Normal Level of Activity
1.9
± 1.2
Functional Comorbidity IndexSecondary· 7 Months
Self-assessment of disease comorbidity with physical function as the outcome. 18 diagnoses are listed and if the participant has been diagnosed with the condition it would be marked at a 1 and if they do not have the condition it would be marked as a zero. Zero would be the fewest amount of co-morbidities and 18 would be the highest amount of co-morbidities.
Baseline (All participants)
Group
Value
95% CI
HOP-UP-PT Program
4.0
± 2.1
Normal Level of Activity
3.9
± 2.3
Baseline (Moderate and High STEADI Risk)
Group
Value
95% CI
HOP-UP-PT Program
4.7
± 2.1
Normal Level of Activity
4.4
± 2.4
3 Month (All participants)
Group
Value
95% CI
HOP-UP-PT Program
4.1
± 2.2
Normal Level of Activity
4.5
± 2.8
3 Month (Moderate and High STEADI Risk)
Group
Value
95% CI
HOP-UP-PT Program
5.1
± 2.43
Normal Level of Activity
5.1
± 3.3
7 Month (All participants)
Group
Value
95% CI
HOP-UP-PT Program
3.8
± 2.6
Normal Level of Activity
4.0
± 2.4
7 Month (Moderate and High STEADI Risk)
Group
Value
95% CI
HOP-UP-PT Program
5.0
± 1.0
Normal Level of Activity
4.6
± 2.8
Home Falls and Accidents Screening Tool (Home FAST)Secondary· 7 Months
The tool evaluates 25 home safety domains and includes questions related to lighting, floor surfaces, and properly fitted foot wear. The original tool design was not scored but the investigators have added a scoring system (13 = safest environment to 50 = least safe environment) to quantify each question pertaining to the home environment. 13 home safety questions are scored as either Yes (indicating the recommended safety modifications was present) or No (indicating the recommended safety modifications had not been met). An additional 12 questions have an N/A option to be used in circumstance
Baseline (All participants)
Group
Value
95% CI
HOP-UP-PT Program
25.7
± 6.2
Normal Level of Activity
25.9
± 7.8
Baseline (Moderate and High STEADI Risk)
Group
Value
95% CI
HOP-UP-PT Program
25.5
± 6.7
Normal Level of Activity
24.9
± 8.6
3 Month (All participants)
Group
Value
95% CI
HOP-UP-PT Program
25.6
± 5.7
Normal Level of Activity
26.8
± 7.3
3 Month (Moderate and High STEADI Risk)
Group
Value
95% CI
HOP-UP-PT Program
25.4
± 6.2
Normal Level of Activity
26.3
± 8.5
7 Month (All participants)
Group
Value
95% CI
HOP-UP-PT Program
26.0
± 5.0
Normal Level of Activity
25.6
± 5.9
7 Month (Moderate and High STEADI Risk)
Group
Value
95% CI
HOP-UP-PT Program
26.9
± 5.7
Normal Level of Activity
23.4
± 5.5
Body Mass IndexSecondary· 7 Months
Assessment of body fat calculated from height and weight.
Baseline (All participants)
Group
Value
95% CI
HOP-UP-PT Program
29.9
± 5.4
Normal Level of Activity
28.6
± 5.4
Baseline (Moderate and High STEADI Risk)
Group
Value
95% CI
HOP-UP-PT Program
30.2
± 5.4
Normal Level of Activity
29.2
± 5.6
7 Month (All participants)
Group
Value
95% CI
HOP-UP-PT Program
29.5
± 5.2
Normal Level of Activity
35.1
± 4.1
7 Month (Moderate and High STEADI Risk)
Group
Value
95% CI
HOP-UP-PT Program
32.7
± 1.1
Normal Level of Activity
30.9
± 6.0
Blood PressureSecondary· 7 Months
Assessment of mean resting blood pressure in seated position.
Baseline (All participants) Systolic
Group
Value
95% CI
HOP-UP-PT Program
133
± 20
Normal Level of Activity
131
± 15
Baseline (All participants) Diastolic
Group
Value
95% CI
HOP-UP-PT Program
76
± 10
Normal Level of Activity
78
± 10
Baseline (Moderate and High STEADI Risk) Systolic
Group
Value
95% CI
HOP-UP-PT Program
133
± 22
Normal Level of Activity
132
± 15
Baseline (Moderate and High STEADI Risk) Diastolic
Group
Value
95% CI
HOP-UP-PT Program
76
± 10
Normal Level of Activity
79
± 12
3 Month (All participants) Systolic
Group
Value
95% CI
HOP-UP-PT Program
125
± 15
Normal Level of Activity
125
± 22
3 Month (All participants) Diastolic
Group
Value
95% CI
HOP-UP-PT Program
76
± 15
Normal Level of Activity
75
± 10
3 Month (Moderate and High STEADI Risk) Systolic
Group
Value
95% CI
HOP-UP-PT Program
123
± 13
Normal Level of Activity
123
± 21
3 Month (Moderate and High STEADI Risk) Diastolic
Group
Value
95% CI
HOP-UP-PT Program
74
± 8
Normal Level of Activity
74
± 7
Number of Participants With Orthostatic HypotensionSecondary· 7 months
Blood pressure was measured sequentially in supine, seated and standing and orthostatic hypotension was determined by the following parameters: a systolic blood pressure decrease of greater than or equal to 20 mm Hg or a diastolic blood pressure decrease of greater than or equal to 10 mm Hg between any of the three positions after three minutes in that position.
Baseline (All participants)
Group
Value
95% CI
HOP-UP-PT Program
13
Normal Level of Activity
16
Baseline (Moderate and High Fall Risk Participants)
Group
Value
95% CI
HOP-UP-PT Program
10
Normal Level of Activity
12
3 Month (All Participants
Group
Value
95% CI
HOP-UP-PT Program
13
Normal Level of Activity
7
3 Month (Moderate and High Fall Risk Participants)
Group
Value
95% CI
HOP-UP-PT Program
4
Normal Level of Activity
3
7 Month (All Participants)
Group
Value
95% CI
HOP-UP-PT Program
10
Normal Level of Activity
5
7 Month (Moderate and High Fall Risk Participants)
Group
Value
95% CI
HOP-UP-PT Program
4
Normal Level of Activity
2
Sponsor's own description
This novel study supports the positive benefits of Home Based Older Persons Upstreaming Physical Therapy (HOP-UP-PT) to older adults identified as "at-risk" by their local senior center after participating in a prevention-focused multimodal program provided by physical therapists in their home.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
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Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Oakland University
Last refreshed: 11 October 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04814459.