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NCT04814082
Prospective Functional, Gait, and Outcome Comparison Study of Medial Pivot Versus Single Radius Design for Total Knee Arthroplasty
NA trial testing MicroPort Evolution Medial-Pivot Knee System (Cruciate-substituting) in Osteoarthritis, Knee in 100 participants. Currently enrolling.
1 July 2030
Quick facts
| Lead sponsor | LifeBridge Health |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 100 |
| Start date | 1 February 2021 |
| Primary completion | 1 July 2030 |
| Estimated completion | 1 July 2030 |
| Sites | 1 location across United States |
Drugs / interventions tested
- MicroPort Evolution Medial-Pivot Knee System (Cruciate-substituting)
- Stryker Triathlon Tritanium Knee System (Condylar Stabilizing)
Conditions studied
- Osteoarthritis, Knee — all drugs for Osteoarthritis, Knee →
- Knee Osteoarthritis — all drugs for Knee Osteoarthritis →
- Osteoarthritis Knees Both — all drugs for Osteoarthritis Knees Both →
- Osteoarthritis Knee Left — all drugs for Osteoarthritis Knee Left →
Sponsor
LifeBridge Health — full company profile →
Who can join
Adults 18 to 75, any sex, with Osteoarthritis, Knee or Knee Osteoarthritis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Patients with degenerative joint disease can effectively be treated with a primary total knee replacement to reduce pain and improve function in their daily lives. Theoretically, achievement of normal knee motion using a medial pivot design in total knee replacements can be recreated in comparison to single radius designs, which could lead to an improvement in post-surgical outcomes and satisfaction with the procedure. The aim of this study is to compare two types of implant designs (medial pivot and single radius) in a total knee replacement using clinical outcomes, patient reported outcomes, and overall function assessed by a specialized gait laboratory.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04814082
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Currently open trials in the same condition.
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- NCT07386561 — Virtual Reality Therapy and Non-Sleep Deep Rest Relaxation After Joint Arthroplasty · NA · active not recruiting
- NCT07514598 — Effect of J-Shaped Incision After Total Knee Arthroplasty (J-TKA) · NA · active not recruiting
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Other LifeBridge Health trials
Trials by the same sponsor.
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- NCT04855175 — Evaluation of Cranioplasty Using Native Bone Autograft Versus Synthetic Bone Allograft · NA · terminated
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04814082 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by LifeBridge Health
- Last refreshed: 22 January 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04814082.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing