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NCT04813965: CONTEXT
Breast Cancer Patients' Cognitive Symptoms After Information About Chemotherapy-Related Cognitive Symptoms
NA trial testing Written information about potential chemotherapy-related cognitive symptoms without self-affirmation in Breast Cancer in 148 participants. Completed in 23 September 2016.
23 September 2016
Quick facts
| Lead sponsor | Radboud University Medical Center |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | supportive care |
| Enrollment | 148 |
| Start date | 20 March 2014 |
| Primary completion | 23 September 2016 |
| Estimated completion | 23 September 2016 |
Drugs / interventions tested
- Written information about potential chemotherapy-related cognitive symptoms without self-affirmation
- Written information about potential chemotherapy-related cognitive symptoms with self-affirmation
Conditions studied
- Breast Cancer — all drugs for Breast Cancer →
- Cognitive Symptoms — all drugs for Cognitive Symptoms →
- Cognitive Decline — all drugs for Cognitive Decline →
Sponsor
Radboud University Medical Center
Who can join
18 and older, any sex, with Breast Cancer or Cognitive Symptoms. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Previous cross-sectional studies have shown that informing cancer patients about potential chemotherapy-related cognitive symptoms may negatively affect perceived cognitive symptoms and verbal memory performance. A multicenter, randomized study in newly diagnosed breast cancer patients receiving (neo) adjuvant chemotherapy was performed to evaluate this Adverse Information Effect (AIE) over time and investigated whether inviting patients to self-affirm can reduce such AIEs on perceived cognitive symptoms and cognitive test performance.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The Effects of Being Informed About Chemotherapy-Related Cognitive Symptoms With And Without Self-Affirmation on Perceived Cognitive Symptoms of Breast Cancer Patients: A Randomized Prospective, Longitudinal Study.
Jacobs W, Schagen SB, Brouwer SM, Kieffer JM, et al · · 2022 · cited 3× · PMID 35491320 · DOI 10.1016/j.clbc.2022.03.001
Verify or expand the search:
- PubMed search for NCT04813965
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04813965 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Radboud University Medical Center
- Last refreshed: 24 March 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04813965.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing