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NCT04811313
Impact of Tranexamic Acid Use on Blood Loss and Transfusion Rates After Hip Reconstruction in Children, A Randomized Controlled Trial
NA trial testing Tranexamic acid in Intraoperative Blood Loss in 400 participants. Currently enrolling.
1 January 2026
Quick facts
| Lead sponsor | Assiut University |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | prevention |
| Enrollment | 400 |
| Start date | 3 April 2025 |
| Primary completion | 1 January 2026 |
| Estimated completion | 1 March 2026 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Tranexamic acid (Tranexamic Acid) — full drug profile →
- caudal epidural block — full drug profile →
- Placebo
Conditions studied
- Intraoperative Blood Loss — all drugs for Intraoperative Blood Loss →
- Pediatric — all drugs for Pediatric →
- Orthopedic Disorder — all drugs for Orthopedic Disorder →
Sponsor
Assiut University
Who can join
Adults 1 to 18, any sex, with Intraoperative Blood Loss or Pediatric. Patients with the condition only — healthy volunteers not accepted.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
-
amount of intraoperative blood loss
Time frame: 24 hours
calculated from the fall in red blood cell volume
Sponsor's own description
Surgical hip reconstruction reduces the hip joint through soft tissue releases and osteotomies of the femur and/or pelvis. Blood loss and subsequent blood transfusion are normal consequences of hip reconstruction.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04811313
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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- NCT06419075 — Tranexamic Acid in Vaginal Reconstructive Surgery · Phase 4 · withdrawn
Other recruiting trials for Intraoperative Blood Loss
Currently open trials in the same condition.
- NCT06399445 — Measurement of Blood Loss in Adenotonsillectomy During General Anesthesia According to the Application of Nondepolarizin · Phase 4 · recruiting
Other Assiut University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04811313 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Assiut University
- Last refreshed: 14 November 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04811313.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing