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Nutraceutical Composition Containing Natural Products Derivatives on the Modulation of the Endocrine Neuroimmune Axis (NCCNPDMENA)
The use of natural products in the prevention or treatment of chronic diseases is an emerging field in current medicine. And studying the mechanisms of actions by which natural products act in our bodies contributes to the rational use of these products. And the combination of different natural products such as prebiotics (FOS- fructooligosaccharides, GOS-Galactooligosaccharides and beta-glucans derived from yeast), herbal medicine (Silybum marianum), and minerals (Se-selenium, Zn-Zinc, and Mg-Magnesium), o which would result in a synergistic association between them can contribute to achieving not only preventive effects but treatment for chronic diseases such as diabetes and obesity. The present study aims to study the effects of a composition containing natural products on factors and markers that are part of mitochondrial biogenesis and the neuroimmune-endocrine system in healthy volunteers and that present grade 1 overweight/obesity.
Details
| Lead sponsor | University of Sao Paulo General Hospital |
|---|---|
| Phase | NA |
| Status | COMPLETED |
| Enrolment | 162 |
| Start date | Thu May 20 2021 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Mon Dec 19 2022 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Insulin Resistance
- Inflammatory Bowel Diseases
- Overweight and Obesity
- Healthy
Interventions
- Composition with Silymarin
- Low-mineral composition without Silymarin
Countries
Brazil