Who is sponsoring ARTHROBTX?

ARTHROBTX is sponsored by Instituto Portugues da Face.

What condition does ARTHROBTX study?

ARTHROBTX studies Temporomandibular Joint Disorders.

What drugs are being tested in ARTHROBTX?

Interventions: Incobotulinumoxin A, TMJ surgical arthroscopy.

What is the status of ARTHROBTX?

ARTHROBTX is currently COMPLETED.

Last reviewed 2022-10-21 · How we verify

Comparison of Temporomandibular Joint Arthroscopy With Botulinum Toxin Injection Versus Placebo (ARTHROBTX)

NCT04810429 PHASE4 COMPLETED

There are several studies that have considered Botulinum toxin A (BoNT-A) injections are effective in treating symptoms for Temporomandibular Joint (TMJ) disorders. BoNT-A injections improve the hyper-tonicity of mandibular muscles and its consequent joint load reduction. Also injections of BoNT-A, for patients with articular disc displacement, resulted in pain relief and return of the normal movements of the mandible. The main goal of this study is to test the beneficial impact of BoNT-A injections in the masticatory muscles of patients submitted to TMJ surgical arthroscopy.

Details

Lead sponsor	Instituto Portugues da Face
Phase	PHASE4
Status	COMPLETED
Enrolment	15
Start date	Fri Jan 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Wed Jun 01 2022 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

Temporomandibular Joint Disorders

Interventions

Incobotulinumoxin A
TMJ surgical arthroscopy

Countries

Portugal