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The Ideal Analgesic Technique for Total Knee Arthroplasty: A Randomized Comparison Between Local Infiltration Analgesia Alone or Combined With Adductor Canal and iPACK Blocks
LIA is the mainstay of postoperative analgesia in patients having knee arthroplasty. The combination of ACB-iPACK blocks has also been proposed as an effective analgesic modality for total knee arthroplasty. However, whether combining these two modalities yields any important incremental analgesic benefit remains unclear. The investigators hypothesized that the addition of ACB and iPACK blocks to LIA will yield clinically important analgesic benefits compared to LIA alone in patients having total knee arthroplasty.
Details
| Lead sponsor | Women's College Hospital |
|---|---|
| Phase | NA |
| Status | NOT_YET_RECRUITING |
| Enrolment | 60 |
| Start date | 2027-01 |
| Completion | 2028-12 |
Conditions
- Nerve Block
- Neuromuscular Blockade
Interventions
- Local infiltration analgesia
- Ultrasound-guided adductor canal block
Primary outcomes
- Postoperative pain at rest — over the first 24 hours
Area under the curve - Quality of recovery (QoR-15) — 24 hours postoperatively
Quality of Recovery (QR15) scores at 24 hours will be the second primary outcome. QR15 is a measurement of quality of recovery after surgery and anesthesia that has been psychometrically tested and validated. Reporting of outcome measures on a scale of 0 to 10 (0=None of the time and 10=All of the time). There are a total of 40 items/questions.