Last reviewed · How we verify
NCT04808388
Using MRI in Patients With Non-dystrophic Myotonia to Access Muscle Contractility
trial testing MRI in Paramyotonia Congenita in 25 participants. Status unknown.
30 December 2021
Quick facts
| Lead sponsor | Rigshospitalet, Denmark |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 25 |
| Start date | 2 February 2021 |
| Primary completion | 30 December 2021 |
| Estimated completion | 31 December 2021 |
| Sites | 1 location across Denmark |
Drugs / interventions tested
- MRI — full drug profile →
Conditions studied
- Paramyotonia Congenita — all drugs for Paramyotonia Congenita →
- Nondystrophic Myotonia — all drugs for Nondystrophic Myotonia →
Sponsor
Rigshospitalet, Denmark
Who can join
18 and older, any sex, with Paramyotonia Congenita or Nondystrophic Myotonia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this project is (1) to investigate whether or not structural muscle abnormalities could be a consequence of the disorder and (2) to provide further clinical description of this rare phenotype. To do so, the investigators will (1) use Dixon MRI to quantify fatty infiltration in muscle tissue and compare it to muscle strength measurements from isometric dynamometry in order to access contractility and (2) describe the myotonic phenotype with simple squeeze test and questionnaires.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Muscle fat replacement and contractility in patients with skeletal muscle sodium channel disorders.
Pedersen JJ, Stemmerik MG, Jacobsen LN, Skriver SV, et al · · 2023 · cited 7× · PMID 36782059 · DOI 10.1038/s41598-023-29759-7
Verify or expand the search:
- PubMed search for NCT04808388
- Europe PMC full search
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04808388 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Rigshospitalet, Denmark
- Last refreshed: 16 September 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04808388.
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