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NCT04806789
Plasma Sodium: a Predictor of Perforation in Acute Appendicitis. (The NAP-study)
trial in Acute Appendicitis in 451 participants. Completed in 25 November 2024.
25 November 2024
Quick facts
| Lead sponsor | Urban Fläring |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 451 |
| Start date | 1 June 2021 |
| Primary completion | 25 November 2024 |
| Estimated completion | 25 November 2024 |
| Sites | 1 location across Sweden |
Conditions studied
- Acute Appendicitis — all drugs for Acute Appendicitis →
- Children, Only — all drugs for Children, Only →
Sponsor
Urban Fläring
Who can join
Adults 1 to 15, any sex, with Acute Appendicitis or Children, Only. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This clinical prospective diagnostic accuracy study assesses plasma sodium concentration using blood gas analysis at the emergency department in children, age 1-15 years, with suspected acute appendicitis. The overall assumption is that using plasma sodium as a biomarker, a cut-off value of \<136 mmol/L will differentiate perforated from non-perforated acute appendicitis. In addition, traditionally used clinical diagnostic variables as well as radiology used in the diagnosis of acute appendicitis will also be obtained. Histopathology will be used to define if the appendix is perforated or not.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04806789
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Acute Appendicitis
Currently open trials in the same condition.
- NCT07496723 — Comparison of Diagnostic Methods in Patients Operated for Suspected Appendicitis · recruiting
- NCT07008092 — Prostaglandin-E Urinary Metabolite (PGE-M) as a Predictor of Acute Appendicitis in Children · recruiting
- NCT07492329 — Antibiotics vs Surgery in Acute Appendicitis · NA · active not recruiting
- NCT06563349 — Magnesium Sulfate in Children Undergoing Laparoscopic Appendectomy · Phase 4 · recruiting
- NCT03236961 — Optimizing the Antibiotic Treatment of Uncomplicated Acute Appendicitis · NA · active not recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04806789 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Urban Fläring
- Last refreshed: 27 November 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04806789.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing