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NCT04805567
Adenoma Miss Rate in Tandem Endocuff-assisted Colonoscopy
trial testing endocuff in Colon Polyp in 150 participants. Status unknown.
1 April 2022
Quick facts
| Lead sponsor | Venizelio General Hospital |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 150 |
| Start date | 1 April 2021 |
| Primary completion | 1 April 2022 |
| Estimated completion | 1 April 2022 |
Drugs / interventions tested
- endocuff
Conditions studied
- Colon Polyp — all drugs for Colon Polyp →
- Endocuff — all drugs for Endocuff →
Sponsor
Venizelio General Hospital
Who can join
50 and older, any sex, with Colon Polyp or Endocuff. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Colonoscopy is a valuable tool in reducing the incidence and mortality from colorectal cancer (CRC). Older back-to-back studies evaluating novel endoscopes indicated that conventional colonoscopy misses almost 20% of adenomas. In order to improve the diagnostic accuracy of colonoscopy and to improve the adenoma detection rate (ADR) (a significant marker of quality), efforts have been made to improve endoscopic techniques, the bowel preparation, to keep slower withdrawal time, and to use new technologies and devices. Since 2012, a new accessory device (Endocuff; ARC Medical Design, Leeds, UK), which is mounted on the tip of the colonoscope has been introduced to the market. The Endocuff is a device that can be mounted on the tip of an endoscope and may assist to inspect a greater surface of the colonic mucosa by pulling backwards, flattening, and stretching the colonic folds as the endoscope is gradually withdrawn. Use of this device may achieve better visualization of the bowel lumen, especially behind folds, and improve stability of the instrument on withdrawal. The aim of this study is to conduct a back-to-back endoscopy study and to evaluate the contribution of Endocuff-assisted colonoscopy to the detection of missed adenomas in a mixed population of colorectal cancer (CRC) screening/surveillance and symptomatic patients.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
Verify or expand the search:
- PubMed search for NCT04805567
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of endocuff
Trials testing the same drug.
- NCT04651062 — Detection of Adenomas in Screening Colonoscopy · NA · completed
Other recruiting trials for Colon Polyp
Currently open trials in the same condition.
- NCT06617468 — Effect of the Computer Aided Diagnosis with Explainable Artificial Intelligence for Colon Polyp on Optical Diagnosis and · NA · active not recruiting
- NCT06496958 — Water Exchange and CO2 Insufflation With Abdominal Compression Device to Reduce Manual Assistance · NA · recruiting
- NCT06073561 — Underwater Endoscopic Mucosal Resection · NA · recruiting
- NCT05990218 — Artificial Intelligence in the Detection of Right Sided Colonic Polyp in Different Operator Experience · NA · recruiting
- NCT05551052 — CRC Detection Reliable Assessment With Blood · active not recruiting
Other Venizelio General Hospital trials
Trials by the same sponsor.
- NCT05191693 — Long-term Outcomes of Endoscopic Papillary Balloon Dilation for 8-12mm Bile Duct Stones: a Prospective Study · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04805567 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Venizelio General Hospital
- Last refreshed: 18 March 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04805567.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing