NCT04803500 is a Phase 2 clinical trial of Simvastatin in Immediate Implant Placement, sponsored by Ain Shams University.

Who is sponsoring NCT04803500?

NCT04803500 is sponsored by Ain Shams University.

What drugs are being tested in NCT04803500?

Interventions in NCT04803500: Simvastatin, Placebo.

What condition does NCT04803500 study?

NCT04803500 studies Immediate Implant Placement, Bone Regeneration, Alveolar Bone Resorption.

Is NCT04803500 still recruiting?

NCT04803500 is currently completed. Last updated 17 March 2021.

Last reviewed 2021-03-17 · How we verify

NCT04803500

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Simvastatin Around Immediate Implant

Completed Phase 2 Last updated 17 March 2021

What this trial tests

Phase 2 trial testing Simvastatin in Immediate Implant Placement in 10 participants. Completed in 3 May 2016.

Timeline

2 April 2015

Primary endpoint
15 February 2016

3 May 2016

Quick facts

Lead sponsor	Ain Shams University
Phase	Phase 2
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	triple
Primary purpose	treatment
Enrollment	10
Start date	2 April 2015
Primary completion	15 February 2016
Estimated completion	3 May 2016

Drugs / interventions tested

Simvastatin (simvastatin) — full drug profile →
Placebo

Conditions studied

Immediate Implant Placement — all drugs for Immediate Implant Placement →
Bone Regeneration — all drugs for Bone Regeneration →
Alveolar Bone Resorption — all drugs for Alveolar Bone Resorption →

Sponsor

Ain Shams University

Who can join

Adults 20 to 50, any sex, with Immediate Implant Placement or Bone Regeneration. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The study evaluated the effect of local application of simvastatin around immediate implant on the amount of gap fill, ridge dimensional alterations and bone density in humans.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Simvastatin

Trials testing the same drug.

NCT07102979 — Remedial Mechanism of Simvastatin and Ursodeoxycholic Acid in Liver Cirrhosis: Crosstalk of Bile Secretion, Gut Microbio · NA · enrolling by invitation
NCT06948747 — A Study to Investigate the Effect of AZD5004 on Rosuvastatin, Atorvastatin, Simvastatin, Repaglinide and the Effect of E · Phase 1 · completed
NCT06858332 — Lipoprotein(a) Levels in Patients With Atherosclerotic Cardiovascular Diseases in Russia · recruiting
NCT07031778 — Topic Simvastatin for Bone Regeneration · EARLY_PHASE1 · recruiting
NCT06399783 — Topical Simvastatin Versus Topical Steroid in Treatment of Alopecia Areata · Phase 4 · not yet recruiting

Other recruiting trials for Immediate Implant Placement

Currently open trials in the same condition.

NCT07492576 — Evaluation of the Magnesium Shield Compared to Dual Zone Grafting Approach in Immediate Implant Site Management · NA · recruiting
NCT07449806 — Assessment of Labial Plate Thickness After Immediate Implant Placement Using Two Different Xenografts in the Esthetic Zo · NA · recruiting
NCT06863051 — Effect of Albumin Platelet-Rich Fibrin or Leucocyte- Platelet-Rich Fibrin on Immediate Implant · NA · recruiting
NCT06842368 — Immediate Implant Placement Using Xenograft Mixed with Vitamin D Versus Hyaluronic Acid. · NA · recruiting
NCT07041294 — Comparing 7 mm and 5 mm Implants Placed Immediately After Molar Extraction · NA · active not recruiting

Other Ain Shams University trials

Trials by the same sponsor.

NCT07435493 — Fentanyl Versus Opioid Free Multimodal Analgesia for Perioperative Pain Control in Children With Mild to Moderate Obstru · NA · not yet recruiting
NCT07482540 — Role of Dexmedatomidine Drug in Prevention of Atrial Fibrillations Post Mitral Valve Surgery · NA · not yet recruiting
NCT07531030 — Posterior Pericapsular Deep Gluteal Block Combined With Pericapsular Nerve Group and Lateral Femoral Cutaneous Nerve Blo · NA · not yet recruiting
NCT06839027 — Arterial to Central co2gap in Relation to Outcome After Cardiopulmonary Bypass · not yet recruiting
NCT07516535 — DISS vs FANS in Suction-Assisted RIRS for Medium-Sized Renal Stones · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04803500 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Ain Shams University
Last refreshed: 17 March 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04803500.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing