NCT04802044 (CARAMEL) is a clinical trial in Covid19, sponsored by Indonesia University.

Who is sponsoring NCT04802044?

NCT04802044 is sponsored by Indonesia University.

What condition does NCT04802044 study?

NCT04802044 studies Covid19, Obesity, Diabetes Mellitus, Aging, Cardiometabolic Syndrome, Immune System Disorder.

Is NCT04802044 still recruiting?

NCT04802044 is currently status unknown. Last updated 18 April 2022.

Last reviewed 2022-04-18 · How we verify

NCT04802044: CARAMEL

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

COVID-19, Aging, and Cardiometabolic Risk Factors Study

Status unknown Last updated 18 April 2022

What this trial tests

trial in Covid19 in 440 participants. Status unknown.

Timeline

8 December 2020

Primary endpoint
31 December 2022

31 December 2023

Quick facts

Lead sponsor	Indonesia University
Status	Status unknown
Study type	OBSERVATIONAL
Enrollment	440
Start date	8 December 2020
Primary completion	31 December 2022
Estimated completion	31 December 2023
Sites	2 locations across Indonesia

Conditions studied

Covid19 — all drugs for Covid19 →
Obesity — all drugs for Obesity →
Diabetes Mellitus — all drugs for Diabetes Mellitus →
Aging — all drugs for Aging →

Sponsor

Indonesia University

Who can join

18 and older, any sex, with Covid19 or Obesity. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

COVID-19 pandemic has made a tremendous impact on Indonesian economic and health care system especially with the double burden of diseases facing by Indonesia as a developing country. The prevalence of non-communicable diseases such as obesity, type diabetes, and cardiovascular diseases is increasing. These diseases along with older age have been known as an established risk factors for higher mortality and severe clinical disease entity in COVID-19 infection. Although, there is still some part of patients with these co-morbidities that only present with mild symptoms when infected with SARS-CoV-2, even for some without any symptoms. Thus, it would be very interesting to evaluate how are these role of aging and cardiometabolic parameters in the clinical disease course of COVID-19 infection, and how are the relationship with the immune system.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Altered Body Composition and Cytokine Production in Patients with Elevated HOMA-IR after SARS-CoV-2 Infection: A 12-Month Longitudinal Study.
Kartika R, Subekti I, Kurniawan F, Wafa S, et al · · 2024 · cited 3× · PMID 39062154 · DOI 10.3390/biomedicines12071581
Reduced IFN-γ-expressing SARS-CoV-2 specific CD4<sup>+</sup> T cells and transient CD8 <sup>+</sup> T cell activation associate with higher HOMA-IR 1-year post COVID-19 in obese individuals.
Kartika R, Tahapary DL, Kurniawan F, Wafa S, et al · · 2025 · PMID 40830616 · DOI 10.1038/s41598-025-11714-3

Verify or expand the search:

Other recruiting trials for Covid19

Currently open trials in the same condition.

NCT03305341 — Proof-of-Concept Clinical Pharmacology Trial for COVID-19 Antigen Presentation Therapeutic Biologic Mix · EARLY_PHASE1 · active not recruiting
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NCT04924803 — Community Developed Technology-Based Messaging to Increase COVID-19 Vaccine Uptake Among People Who Inject Drugs · NA · active not recruiting
NCT05013632 — COVID-19 International Drug Pregnancy Registry · recruiting
NCT04806061 — Urine Alkalinisation in COVID-19 · NA · active not recruiting

Other Indonesia University trials

Trials by the same sponsor.

NCT07137130 — Secretome TGF Beta 3 · NA · not yet recruiting
NCT07420335 — Preoperative Shoulder Exercises and Postoperative Inflammation, Pain, and Function After Modified Radical Mastectomy · NA · not yet recruiting
NCT07278284 — The Effectiveness of Press Needle Acupuncture on Preoperative Anxiety in Tympanoplasty and Mastoidectomy · NA · recruiting
NCT07337187 — Effect of Thread-Embedding Acupuncture at EX-B2 on Pain and Quality of Life in Chronic Low Back Pain · NA · not yet recruiting
NCT07242001 — Laser Acupuncture for Otitis Media With Effusion in Children · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04802044 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Indonesia University
Last refreshed: 18 April 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04802044.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing