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NCT04800081

Effect of LCZ696 on Urinary Microalbumin and Pulse Wave Velocity in Perimenopausal Patients With Hypertension

Status unknown NA Last updated 16 March 2021
What this trial tests

NA trial testing Sacubitril/Valsartan in Hypertension in 264 participants. Status unknown.

Timeline
9 July 2020
Primary endpoint
9 June 2021
9 July 2021

Quick facts

Lead sponsorLanZhou University
PhaseNA
StatusStatus unknown
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingnone
Primary purposetreatment
Enrollment264
Start date9 July 2020
Primary completion9 June 2021
Estimated completion9 July 2021
Sites1 location across China

Drugs / interventions tested

Conditions studied

Sponsor

LanZhou University

Who can join

Adults 40 to 60, female only, with Hypertension. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

To explore the efficacy of Sacubitril/Valsartan in the treatment of perimenopausal hypertensive patients, as well as the difference between the antihypertensive efficacy and valsartan, the therapeutic effect of its exposure to different factors and the protection of target organs.To provide reference for the clinical treatment of perimenopausal hypertension patients with shakubactrivalsartan. 1. To evaluate the effects of Sacubitril/Valsartan on urinary microalbumin and pulse wave velocity in perimenopausal hypertension patients. 2. To evaluate the clinical application of Sacubitril/Valsartan in the treatment of perimenopausal hypertension, so as to improve the blood pressure management ability and control rate of patients with such hypertension.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Effect of sacubitril/valsartan or valsartan on ventricular remodeling and myocardial fibrosis in perimenopausal women with hypertension.
    Chen J, Pei Y, Wang Q, Li C, et al · · 2023 · cited 9× · PMID 37071432 · DOI 10.1097/hjh.0000000000003430

Verify or expand the search:

Other trials of Sacubitril/Valsartan

Trials testing the same drug.

Other recruiting trials for Hypertension

Currently open trials in the same condition.

Other LanZhou University trials

Trials by the same sponsor.

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Data sources for this page

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