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NCT04800081
Effect of LCZ696 on Urinary Microalbumin and Pulse Wave Velocity in Perimenopausal Patients With Hypertension
NA trial testing Sacubitril/Valsartan in Hypertension in 264 participants. Status unknown.
9 June 2021
Quick facts
| Lead sponsor | LanZhou University |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 264 |
| Start date | 9 July 2020 |
| Primary completion | 9 June 2021 |
| Estimated completion | 9 July 2021 |
| Sites | 1 location across China |
Drugs / interventions tested
- Sacubitril/Valsartan
- Valsartan (VALSARTAN) — full drug profile →
Conditions studied
- Hypertension — all drugs for Hypertension →
Sponsor
LanZhou University
Who can join
Adults 40 to 60, female only, with Hypertension. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To explore the efficacy of Sacubitril/Valsartan in the treatment of perimenopausal hypertensive patients, as well as the difference between the antihypertensive efficacy and valsartan, the therapeutic effect of its exposure to different factors and the protection of target organs.To provide reference for the clinical treatment of perimenopausal hypertension patients with shakubactrivalsartan. 1. To evaluate the effects of Sacubitril/Valsartan on urinary microalbumin and pulse wave velocity in perimenopausal hypertension patients. 2. To evaluate the clinical application of Sacubitril/Valsartan in the treatment of perimenopausal hypertension, so as to improve the blood pressure management ability and control rate of patients with such hypertension.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Effect of sacubitril/valsartan or valsartan on ventricular remodeling and myocardial fibrosis in perimenopausal women with hypertension.
Chen J, Pei Y, Wang Q, Li C, et al · · 2023 · cited 9× · PMID 37071432 · DOI 10.1097/hjh.0000000000003430
Verify or expand the search:
- PubMed search for NCT04800081
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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- NCT04736433 — Replication of the PARADIGM-HF Heart Failure Trial in Healthcare Claims Data. · completed
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Other recruiting trials for Hypertension
Currently open trials in the same condition.
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Other LanZhou University trials
Trials by the same sponsor.
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- NCT07234344 — A Predictive Model for Midwives' C F: A Cross-Sectional Study · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04800081 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by LanZhou University
- Last refreshed: 16 March 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04800081.
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