Last reviewed · How we verify
NCT04799171: MoTrMito
Aging and the Mitochondrial Response to Exercise Training, Measured by Noninvasive 31P Magnetic Resonance Spectroscopy
NA trial testing Isometric Contraction Exercise - Young Adults (Age group 18-39) in Physical Activity in 352 participants. Completed in 12 May 2025.
12 May 2025
Quick facts
| Lead sponsor | Pennington Biomedical Research Center |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | other |
| Enrollment | 352 |
| Start date | 2 August 2021 |
| Primary completion | 12 May 2025 |
| Estimated completion | 12 May 2025 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Isometric Contraction Exercise - Young Adults (Age group 18-39)
- Isometric Contraction Exercise - Middle Age Adults (Age group 40-59)
- Isometric Contraction Exercise - Old Adults (Age group >60)
Conditions studied
- Physical Activity — all drugs for Physical Activity →
Sponsor
Pennington Biomedical Research Center — full company profile →
Who can join
18 and older, any sex, with Physical Activity. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of the study is to determine whether aerobic or resistant exercise can improve in vivo mitochondrial capacity of skeletal muscle cells similarly in healthy younger, middle aged and older adults. This confers long-term changes in this tissue which in-turn contribute to improved metabolic health and functional capacity through epigenetic regulation of novel exercise response genes.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04799171
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Physical Activity
Currently open trials in the same condition.
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- NCT07466914 — Constipation in Children With Cerebral Palsy · active not recruiting
- NCT07290309 — Survivors Uniting for Remote Guided Exercise · NA · recruiting
- NCT07415460 — Evaluating the Impact of SKY Breath Meditation on Stress, Well-being, and Connection in College Students · NA · recruiting
- NCT07585409 — Physical Activity in Persons With Parkinson's Disease · recruiting
Other Pennington Biomedical Research Center trials
Trials by the same sponsor.
- NCT07530718 — Body Composition Outcomes in MS Patients · not yet recruiting
- NCT07095972 — Continuous Glucose Monitoring in Metabolic Surgery · NA · not yet recruiting
- NCT07139821 — Dietary Iron Requirements · recruiting
- NCT07318064 — Ultra-processed Food Consumption and Health Pilot Study · NA · not yet recruiting
- NCT07305753 — CanCan Body Composition Study · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04799171 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Pennington Biomedical Research Center
- Last refreshed: 22 August 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04799171.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing