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NCT04794153: FFT

Investigating the Consumption of Different Protein Rich Whole Food Sources on Muscle Growth in Trained Males and Females

Completed NA Last updated 9 May 2024
What this trial tests

NA trial testing whole food sources in Nutritional Intervention Using Protein Rich Whole Food Sources in 66 participants. Completed in 1 May 2024.

Timeline
1 May 2021
Primary endpoint
1 April 2024
1 May 2024

Quick facts

Lead sponsorUniversity of Exeter
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingnone
Primary purposeother
Enrollment66
Start date1 May 2021
Primary completion1 April 2024
Estimated completion1 May 2024
Sites1 location across United Kingdom

Drugs / interventions tested

Conditions studied

Sponsor

University of Exeter

Who can join

Adults 18 to 40, any sex, with Nutritional Intervention Using Protein Rich Whole Food Sources. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Background To date, most of the literature investigating the role of dietary protein in muscle growth has focused on isolated protein sources. However, dietary protein is most commonly consumed within a whole food source. Consuming dietary protein within a whole food matrix may additionally stimulate muscle growth. The idea being, there may be other components within food, capable of producing a greater response. Objectives: To assess the effect of consuming a variety of whole food sources, on the stimulation of muscle growth compared to an isolated protein source following a single bout of lower body resistance exercise. Methods Young healthy resistance-trained volunteers will consume a protein rich whole food source, following a bout of lower body resistance exercise. Stable isotope IV infusions and repeated blood and muscle samples will be taken to assess protein digestion and absorption, as well as muscle protein synthesis rates. Value of Research: To determine whether whole food sources potentiate muscle protein synthesis rates (and to what extent across whole food sources) compared to an isolated protein source. In doing so, we can further investigate the nutrients involved that may be contributing to this effect.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Ingestion of diverse protein-rich whole-foods result in similar post exercise whole body and myofibrillar protein synthesis rates compared with a more isolated protein source in young adults.
    Haigh FA, Monteyne AJ, Abdelrahman DR, Murton AJ, et al · · 2026 · PMID 41643855 · DOI 10.1016/j.ajcnut.2026.101231

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