Who is sponsoring NCT04792983?

NCT04792983 is sponsored by Brigham and Women's Hospital.

What condition does NCT04792983 study?

NCT04792983 studies Cognitive Impairment, Frail Elderly Syndrome, Delirium, Surgery.

What drugs are being tested in NCT04792983?

Interventions: No intervention.

What is the status of NCT04792983?

NCT04792983 is currently UNKNOWN.

Last reviewed 2021-03-12 · How we verify

Cognition and the Immunology of Postoperative Outcomes

NCT04792983 UNKNOWN

This research will test the hypothesis that immune system disequilibrium / dysfunction explains why preoperative cognitive impairment is a strong predictor of postoperative morbidity in older surgical patients. The investigators propose that cognitive impairment influences surgical morbidity because of underlying immune disequilibrium / dysfunction (risk marker) and that this shapes the immune response to surgery and defines immunological hallmarks of postoperative morbidity (disease marker). The overarching goal of this application therefore is to define and better understand the clinical immunology underlying the relationship between cognition and geriatric surgical morbidity.

Details

Lead sponsor	Brigham and Women's Hospital
Status	UNKNOWN
Enrolment	600
Start date	Fri Sep 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Thu Jul 31 2025 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

Cognitive Impairment
Frail Elderly Syndrome
Delirium
Surgery

Interventions

No intervention

Countries

United States